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World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update – I – Plan and definitions

  • the WAO DRACMA guideline group
  • IRCCS Ospedale pediatrico Bambino Gesù - Roma
  • McMaster University
  • Hamilton Health Sciences
  • National Hospital Organization Sagamihara National Hospital
  • Hospital Quirónsalud Bizkaia
  • Cincinnati Children's Hospital Medical Center
  • LSU Health Sciences Center - Shreveport
  • University of Naples Federico II
  • Hospital Británico de Buenos Aires
  • Université Paris Cité
  • UNIFACISA University Centre
  • Fatebenefratelli Hospital
  • Aga Khan University
  • King's College London
  • Guy's and St Thomas' NHS Foundation Trust
  • Chongqing Medical University
  • Italian Society of Pediatric Allergy and Immunology
  • New York University
  • University of Warmia and Mazury in Olsztyn
  • National and Kapodistrian University of Athens
  • University of Manchester
  • Nippon Medical School
  • Allergy & Anaphylaxis Australia (A&AA)
  • Centro Medico-Docente La Trinidad
  • Schneider Childrens Medical Center Israel
  • Tel Aviv University
  • University of Pennsylvania
  • Medical University of Warsaw
  • Italian NHS and Italian Society of Social and Preventive Pediatrics
  • Vrije Universiteit Brussel
  • University of Colorado Anschutz Medical Campus
  • Allergy UK
  • Chinese University of Hong Kong

Research output: Contribution to journalArticlepeer-review

65 Scopus citations

Abstract

Since the World Allergy Organization (WAO) Diagnosis and Rationale against Cow's Milk Allergy (DRACMA) Guidelines were published 10 years ago, new evidence has accumulated about the diagnosis, therapy, and specific immunotherapy for cow's milk allergy (CMA). For this reason, WAO has felt the need to update the guidelines. We introduce here this update. The new DRACMA guidelines aim to comprehensively address the guidance on diagnosis and therapy of both IgE non-IgE-mediated forms of cow's milk allergy in children and adults. They will be divided into 18 chapters, each of which will be dedicated to an aspect. The focus will be on the meta-analyzes and recommendations that will be expressed for the 3 most relevant clinical aspects: (a) the diagnostic identification of the condition; (b) the choice of the replacement formula in case of CMA in infancy when the mother is not able to breastfeed, and (c) the use of specific immunotherapy for cow's milk protein allergy.

Original languageEnglish
Article number100609
JournalWorld Allergy Organization Journal
Volume15
Issue number1
DOIs
StatePublished - Jan 2022

Keywords

  • Cow's milk allergy
  • Food allergy
  • GRADE
  • Oral immunotherapy

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