Wiring the zebrafish: Axon guidance and synaptogenesis

Lara D. Hutson; Chi Bin Chien

doi:10.1016/S0959-4388(02)00294-5

Wiring the zebrafish: Axon guidance and synaptogenesis

Lara D. Hutson
, Chi Bin Chien

Biological Sciences

University of Utah

Research output: Contribution to journal › Review article › peer-review

43 Scopus citations

Abstract

Many zebrafish mutants have specific defects in axon guidance or synaptogenesis, particularly in the retinotectal and motor systems. Several mutants have now been characterized in detail and/or cloned. A combination of genetic studies, in vivo imaging and new techniques for misexpressing genes or blocking their function promises to reveal the molecules and principles that govern wiring of the vertebrate nervous system.

Original language	English
Pages (from-to)	87-92
Number of pages	6
Journal	Current Opinion in Neurobiology
Volume	12
Issue number	1
DOIs	https://doi.org/10.1016/S0959-4388(02)00294-5
State	Published - Feb 1 2002

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title = "Wiring the zebrafish: Axon guidance and synaptogenesis",

abstract = "Many zebrafish mutants have specific defects in axon guidance or synaptogenesis, particularly in the retinotectal and motor systems. Several mutants have now been characterized in detail and/or cloned. A combination of genetic studies, in vivo imaging and new techniques for misexpressing genes or blocking their function promises to reveal the molecules and principles that govern wiring of the vertebrate nervous system.",

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N2 - Many zebrafish mutants have specific defects in axon guidance or synaptogenesis, particularly in the retinotectal and motor systems. Several mutants have now been characterized in detail and/or cloned. A combination of genetic studies, in vivo imaging and new techniques for misexpressing genes or blocking their function promises to reveal the molecules and principles that govern wiring of the vertebrate nervous system.

AB - Many zebrafish mutants have specific defects in axon guidance or synaptogenesis, particularly in the retinotectal and motor systems. Several mutants have now been characterized in detail and/or cloned. A combination of genetic studies, in vivo imaging and new techniques for misexpressing genes or blocking their function promises to reveal the molecules and principles that govern wiring of the vertebrate nervous system.

UR - https://www.scopus.com/pages/publications/0036471679

U2 - 10.1016/S0959-4388(02)00294-5

DO - 10.1016/S0959-4388(02)00294-5

M3 - Review article

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JO - Current Opinion in Neurobiology

JF - Current Opinion in Neurobiology

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Wiring the zebrafish: Axon guidance and synaptogenesis

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