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Very-high-dose methadone with minimal toxicity and inadequate pain control in a hospice patient with cancer

  • Center for Hospice and Palliative Care

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A case is reported of a 48-year-old Caucasian male who was admitted to hospice care with metastatic cancer of the larynx. The patient required very high methadone doses and experienced little opioid toxicity. The pharmacodynamics and pharmacokinetics of methadone are discussed in the context of this patient experience.

Original languageEnglish
Pages (from-to)143-149
Number of pages7
JournalJournal of Pain and Palliative Care Pharmacotherapy
Volume27
Issue number2
DOIs
StatePublished - Jun 2013

Keywords

  • Cancer
  • High dose
  • Hospice
  • Methadone
  • Pain
  • Palliative

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