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Vertical transmission of histoplasmosis associated with anti-tumor necrosis factor therapy

  • James G. Carlucci
  • , Natasha Halasa
  • , C. Buddy Creech
  • , Daniel E. Dulek
  • , Oscar G. Gómez-Duarte
  • , George E. Nelson
  • , H. Keipp Talbot
  • , Melissa L. Scalise
  • , Patricia L. Scott
  • , Uma Mahadevan
  • , Dawn B. Beaulieu
  • Vanderbilt University
  • Tennessee Maternal Fetal Medicine
  • University of California at San Francisco

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Therapeutics blocking the activity of tumor necrosis factor (anti-TNF) are a risk factor for invasive fungal infections; however, infectious risks to infants born to mothers receiving anti-TNF therapy are not well defined. We report a case of vertical transmission of disseminated histoplasmosis in a mother-infant pair exposed to anti- TNF therapy.

Original languageEnglish
Article numberpiw001
Pages (from-to)e9-e12
JournalJournal of the Pediatric Infectious Diseases Society
Volume5
Issue number2
DOIs
StatePublished - Jun 10 2016

Keywords

  • Histoplasmosis
  • Immunocompromised host
  • Infant
  • Tumor necrosis factor
  • Vertical transmission

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