Verapamil: A new antimanic drug with potential interactions with lithium

S. L. Dubovsky; R. D. Franks; S. Allen

Verapamil: A new antimanic drug with potential interactions with lithium

S. L. Dubovsky
, R. D. Franks
, S. Allen

Department of Psychiatry

University of Colorado Anschutz Medical Campus

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Verapamil is a calcium channel blocking agent with possible antimanic properties. In two elderly manic patients taking the medication in combination with lithium carbonate, profound bradycardia developed and was followed by a fatal myocardial infarction in one case. Clinical implications and possible mechanisms of cardiovascular interactions between verapamil and lithium are discussed. Caution is advised in the use of lithium and verapamil together.

Original language	English
Pages (from-to)	371-372
Number of pages	2
Journal	Journal of Clinical Psychiatry
Volume	48
Issue number	9
State	Published - 1987

Cite this

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title = "Verapamil: A new antimanic drug with potential interactions with lithium",

abstract = "Verapamil is a calcium channel blocking agent with possible antimanic properties. In two elderly manic patients taking the medication in combination with lithium carbonate, profound bradycardia developed and was followed by a fatal myocardial infarction in one case. Clinical implications and possible mechanisms of cardiovascular interactions between verapamil and lithium are discussed. Caution is advised in the use of lithium and verapamil together.",

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year = "1987",

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T2 - A new antimanic drug with potential interactions with lithium

AU - Dubovsky, S. L.

AU - Franks, R. D.

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N2 - Verapamil is a calcium channel blocking agent with possible antimanic properties. In two elderly manic patients taking the medication in combination with lithium carbonate, profound bradycardia developed and was followed by a fatal myocardial infarction in one case. Clinical implications and possible mechanisms of cardiovascular interactions between verapamil and lithium are discussed. Caution is advised in the use of lithium and verapamil together.

AB - Verapamil is a calcium channel blocking agent with possible antimanic properties. In two elderly manic patients taking the medication in combination with lithium carbonate, profound bradycardia developed and was followed by a fatal myocardial infarction in one case. Clinical implications and possible mechanisms of cardiovascular interactions between verapamil and lithium are discussed. Caution is advised in the use of lithium and verapamil together.

UR - https://www.scopus.com/pages/publications/0023270334

M3 - Article

C2 - 3114243

AN - SCOPUS:0023270334

SN - 0160-6689

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JO - Journal of Clinical Psychiatry

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ER -

Verapamil: A new antimanic drug with potential interactions with lithium

Abstract

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