Tunable multicolored hybrid metallic nanoparticles for live human cancer cell imaging

Rui Hu; Ken Tye Yong; Hong Ding; Paras N. Prasad; Sailing He

doi:10.1117/1.3361662

Tunable multicolored hybrid metallic nanoparticles for live human cancer cell imaging

Rui Hu
, Ken Tye Yong
, Hong Ding
, Paras N. Prasad
, Sailing He

Chemistry

Zhejiang University
SUNY Buffalo
KTH Royal Institute of Technology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Gold/silver core/shell nanorods with precisely tunable resonance peaks covering the visible and near-infrared wavelength range were obtained using a simple wet-chemical synthesis approach. These nanoparticles surfaces can be further modified to improve their biocompatibility and stability in biological media. After conjugating with some biomolecules, these functionalized nanoparticles were used as multicolored optical probes for targeted dark field imaging of live human cancer cells. These experiments suggest that the gold/silver core/shell nanoparticles can serve as a potential platform for multichanneled and ultrasensitive bioimaging.

Original language	English
Article number	041545
Journal	Journal of Nanophotonics
Volume	4
Issue number	1
DOIs	https://doi.org/10.1117/1.3361662
State	Published - 2010

Keywords

bioimaging
cancer
core/shell nanorods
metallic nanoparticles
multichannel
scattering

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10.1117/1.3361662

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title = "Tunable multicolored hybrid metallic nanoparticles for live human cancer cell imaging",

abstract = "Gold/silver core/shell nanorods with precisely tunable resonance peaks covering the visible and near-infrared wavelength range were obtained using a simple wet-chemical synthesis approach. These nanoparticles surfaces can be further modified to improve their biocompatibility and stability in biological media. After conjugating with some biomolecules, these functionalized nanoparticles were used as multicolored optical probes for targeted dark field imaging of live human cancer cells. These experiments suggest that the gold/silver core/shell nanoparticles can serve as a potential platform for multichanneled and ultrasensitive bioimaging.",

keywords = "bioimaging, cancer, core/shell nanorods, metallic nanoparticles, multichannel, scattering",

author = "Rui Hu and Yong, \{Ken Tye\} and Hong Ding and Prasad, \{Paras N.\} and Sailing He",

year = "2010",

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language = "English",

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T1 - Tunable multicolored hybrid metallic nanoparticles for live human cancer cell imaging

AU - Hu, Rui

AU - Yong, Ken Tye

AU - Ding, Hong

AU - Prasad, Paras N.

AU - He, Sailing

PY - 2010

Y1 - 2010

N2 - Gold/silver core/shell nanorods with precisely tunable resonance peaks covering the visible and near-infrared wavelength range were obtained using a simple wet-chemical synthesis approach. These nanoparticles surfaces can be further modified to improve their biocompatibility and stability in biological media. After conjugating with some biomolecules, these functionalized nanoparticles were used as multicolored optical probes for targeted dark field imaging of live human cancer cells. These experiments suggest that the gold/silver core/shell nanoparticles can serve as a potential platform for multichanneled and ultrasensitive bioimaging.

AB - Gold/silver core/shell nanorods with precisely tunable resonance peaks covering the visible and near-infrared wavelength range were obtained using a simple wet-chemical synthesis approach. These nanoparticles surfaces can be further modified to improve their biocompatibility and stability in biological media. After conjugating with some biomolecules, these functionalized nanoparticles were used as multicolored optical probes for targeted dark field imaging of live human cancer cells. These experiments suggest that the gold/silver core/shell nanoparticles can serve as a potential platform for multichanneled and ultrasensitive bioimaging.

KW - bioimaging

KW - cancer

KW - core/shell nanorods

KW - metallic nanoparticles

KW - multichannel

KW - scattering

UR - https://www.scopus.com/pages/publications/80455156134

U2 - 10.1117/1.3361662

DO - 10.1117/1.3361662

M3 - Article

AN - SCOPUS:80455156134

SN - 1934-2608

VL - 4

JO - Journal of Nanophotonics

JF - Journal of Nanophotonics

IS - 1

M1 - 041545

ER -

Tunable multicolored hybrid metallic nanoparticles for live human cancer cell imaging

Abstract

Keywords

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