Abstract
In addition to indole-3-glycerolphosphate, an unreported reaction product has been detected in incubation mixtures containing tryptophan synthetase from Neurospora, indole, and glyceraldehyde-3-phosphate. This product has been tentatively identified as an indole derivative. Since this compound is not formed in incubation mixtures initially containing only enzyme and indole-3-glycerolphosphate, it was concluded that indole-3-glycerolphosphate synthesis and breakdown are not simply the forward and reverse components of a reversible reaction.
| Original language | English |
|---|---|
| Pages (from-to) | 491-492 |
| Number of pages | 2 |
| Journal | Science |
| Volume | 145 |
| Issue number | 3631 |
| DOIs | |
| State | Published - 1964 |
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