TY - GEN
T1 - Towards a proteomics meta-classification
AU - Kumar, Anand
AU - Smith, Barry
PY - 2004
Y1 - 2004
N2 - There is a recognized need for a meta-classification that can serve as a foundation for more refined ontologies in the field of proteomics. Standard data sources classify proteins in terms of just one or two specific aspects. Thus SCOP (Structural Classification of Proteins) is described as classifying proteins on the basis of structural features; SWISS-PROT annotates proteins on the basis of their structure and of parameters like post-translational modifications. Such data sources are connected to each other by pairwise term-to-term mappings. However, there are obstacles which stand in the way of combining them together to form a robust meta-classification of the needed sort. We discuss some formal ontological principles which should be taken into account within the existing datasources in order to make such a meta-classification possible, taking into account also the Gene Ontology (GO) and its application to the annotation of proteins.
AB - There is a recognized need for a meta-classification that can serve as a foundation for more refined ontologies in the field of proteomics. Standard data sources classify proteins in terms of just one or two specific aspects. Thus SCOP (Structural Classification of Proteins) is described as classifying proteins on the basis of structural features; SWISS-PROT annotates proteins on the basis of their structure and of parameters like post-translational modifications. Such data sources are connected to each other by pairwise term-to-term mappings. However, there are obstacles which stand in the way of combining them together to form a robust meta-classification of the needed sort. We discuss some formal ontological principles which should be taken into account within the existing datasources in order to make such a meta-classification possible, taking into account also the Gene Ontology (GO) and its application to the annotation of proteins.
UR - https://www.scopus.com/pages/publications/4544299739
U2 - 10.1109/BIBE.2004.1317373
DO - 10.1109/BIBE.2004.1317373
M3 - Conference contribution
AN - SCOPUS:4544299739
SN - 0769521738
SN - 9780769521732
T3 - Proceedings - Fourth IEEE Symposium on Bioinformatics and Bioengineering, BIBE 2004
SP - 419
EP - 426
BT - Proceedings - Fourth IEEE Symposium on Bioinformatics and Bioengineering, BIBE 2004
T2 - Proceedings - Fourth IEEE Symposium on Bioinformatics and Bioengineering, BIBE 2004
Y2 - 19 May 2004 through 21 May 2004
ER -