Tools to rapidly produce and screen biodegradable polymer and sol-gel-derived xerogel formulations

Eun Jeong Cho; Zunyu Tao; Ying Tang; Elizabeth C. Tehan; Frank V. Bright; Wesley L. Hicks; Joseph A. Gardella; Robert Hard

doi:10.1366/00037020260377661

Tools to rapidly produce and screen biodegradable polymer and sol-gel-derived xerogel formulations

Eun Jeong Cho
, Zunyu Tao
, Ying Tang
, Elizabeth C. Tehan
, Frank V. Bright
, Wesley L. Hicks
, Joseph A. Gardella
, Robert Hard

SUNY Buffalo
Roswell Park Cancer Institute

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

A new method to rapidly produce and screen biodegradable polymer- and xerogel-based formulations is described. The approach is based on a high-speed pin printer and imaging with an epi-fluorescence microscope/charge-coupled device detector. By using this approach we can produce and screen over 600 formulations/h and rapidly identify lead formulations and/or compositions that are the most useful for the development of biodegradable devices or (bio)sensors.

Original language	English
Pages (from-to)	1385-1389
Number of pages	5
Journal	Applied Spectroscopy
Volume	56
Issue number	11
DOIs	https://doi.org/10.1366/00037020260377661
State	Published - Nov 2002

Keywords

Biodegradable polymers
Keratinocyte growth factor
Monoclonal anti-fluorescein antibodies
Protein activity
Protein-doped xerogels
Rapid screening

Access to Document

10.1366/00037020260377661

Cite this

@article{6d369f09715042988df24db6fa42006a,

title = "Tools to rapidly produce and screen biodegradable polymer and sol-gel-derived xerogel formulations",

abstract = "A new method to rapidly produce and screen biodegradable polymer- and xerogel-based formulations is described. The approach is based on a high-speed pin printer and imaging with an epi-fluorescence microscope/charge-coupled device detector. By using this approach we can produce and screen over 600 formulations/h and rapidly identify lead formulations and/or compositions that are the most useful for the development of biodegradable devices or (bio)sensors.",

keywords = "Biodegradable polymers, Keratinocyte growth factor, Monoclonal anti-fluorescein antibodies, Protein activity, Protein-doped xerogels, Rapid screening",

author = "Cho, \{Eun Jeong\} and Zunyu Tao and Ying Tang and Tehan, \{Elizabeth C.\} and Bright, \{Frank V.\} and Hicks, \{Wesley L.\} and Gardella, \{Joseph A.\} and Robert Hard",

year = "2002",

month = nov,

doi = "10.1366/00037020260377661",

language = "English",

volume = "56",

pages = "1385--1389",

journal = "Applied Spectroscopy",

issn = "0003-7028",

publisher = "SAGE Publications Inc.",

number = "11",

}

TY - JOUR

T1 - Tools to rapidly produce and screen biodegradable polymer and sol-gel-derived xerogel formulations

AU - Cho, Eun Jeong

AU - Tao, Zunyu

AU - Tang, Ying

AU - Tehan, Elizabeth C.

AU - Bright, Frank V.

AU - Hicks, Wesley L.

AU - Gardella, Joseph A.

AU - Hard, Robert

PY - 2002/11

Y1 - 2002/11

N2 - A new method to rapidly produce and screen biodegradable polymer- and xerogel-based formulations is described. The approach is based on a high-speed pin printer and imaging with an epi-fluorescence microscope/charge-coupled device detector. By using this approach we can produce and screen over 600 formulations/h and rapidly identify lead formulations and/or compositions that are the most useful for the development of biodegradable devices or (bio)sensors.

AB - A new method to rapidly produce and screen biodegradable polymer- and xerogel-based formulations is described. The approach is based on a high-speed pin printer and imaging with an epi-fluorescence microscope/charge-coupled device detector. By using this approach we can produce and screen over 600 formulations/h and rapidly identify lead formulations and/or compositions that are the most useful for the development of biodegradable devices or (bio)sensors.

KW - Biodegradable polymers

KW - Keratinocyte growth factor

KW - Monoclonal anti-fluorescein antibodies

KW - Protein activity

KW - Protein-doped xerogels

KW - Rapid screening

UR - https://www.scopus.com/pages/publications/0036869022

U2 - 10.1366/00037020260377661

DO - 10.1366/00037020260377661

M3 - Article

AN - SCOPUS:0036869022

SN - 0003-7028

VL - 56

SP - 1385

EP - 1389

JO - Applied Spectroscopy

JF - Applied Spectroscopy

IS - 11

ER -

Tools to rapidly produce and screen biodegradable polymer and sol-gel-derived xerogel formulations

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this