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Tissue regeneration with photobiomodulation

  • National Institutes of Health

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

Low level light therapy (LLLT) has been widely reported to reduce pain and inflammation and enhance wound healing and tissue regeneration in various settings. LLLT has been noted to have both stimulatory and inhibitory biological effects and these effects have been termed Photobiomodulation (PBM). Several elegant studies have shown the key role of Cytochrome C oxidase and ROS in initiating this process. The downstream biological responses remain to be clearly elucidated. Our work has demonstrated activation of an endogenous latent growth factor complex, TGF-β1, as one of the major biological events in PBM. TGF-β1 has critical roles in various biological processes especially in inflammation, immune responses, wound healing and stem cell biology. This paper overviews some of the studies demonstrating the efficacy of PBM in promoting tissue regeneration.

Original languageEnglish
Title of host publicationMechanisms for Low-Light Therapy VIII
DOIs
StatePublished - 2013
EventMechanisms for Low-Light Therapy VIII - San Francisco, CA, United States
Duration: Feb 2 2013 → Feb 2 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8569
ISSN (Print)1605-7422

Conference

ConferenceMechanisms for Low-Light Therapy VIII
Country/TerritoryUnited States
CitySan Francisco, CA
Period02/2/13 → 02/2/13

Keywords

  • Low level light therapy
  • Photobiomodulation
  • Tissue regeneration
  • Wound healing

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