The synthesis of amidine acetals as intermediates for the preparation of naturally occurring cyclic amidine antibiotics

Wayne K. Anderson; Natarangan Raju

doi:10.1080/00397918908052621

The synthesis of amidine acetals as intermediates for the preparation of naturally occurring cyclic amidine antibiotics

Wayne K. Anderson
, Natarangan Raju

Pharmaceutical Sciences

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Regioselective 1,3-dipolar cycloaddition of (phenylsulfonyl)nitrile oxide to acrolein dimethylacetal gave the isoxazole 3. Nucleophilic displacement of the phenylsulfonyl moiety followed by reductive N-O bond cleavage gave the amidine acetal 6.

Original language	English
Pages (from-to)	2237-2242
Number of pages	6
Journal	Synthetic Communications
Volume	19
Issue number	13-14
DOIs	https://doi.org/10.1080/00397918908052621
State	Published - Aug 1989

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title = "The synthesis of amidine acetals as intermediates for the preparation of naturally occurring cyclic amidine antibiotics",

abstract = "Regioselective 1,3-dipolar cycloaddition of (phenylsulfonyl)nitrile oxide to acrolein dimethylacetal gave the isoxazole 3. Nucleophilic displacement of the phenylsulfonyl moiety followed by reductive N-O bond cleavage gave the amidine acetal 6.",

author = "Anderson, \{Wayne K.\} and Natarangan Raju",

year = "1989",

month = aug,

doi = "10.1080/00397918908052621",

language = "English",

volume = "19",

pages = "2237--2242",

journal = "Synthetic Communications",

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number = "13-14",

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T1 - The synthesis of amidine acetals as intermediates for the preparation of naturally occurring cyclic amidine antibiotics

AU - Anderson, Wayne K.

AU - Raju, Natarangan

PY - 1989/8

Y1 - 1989/8

N2 - Regioselective 1,3-dipolar cycloaddition of (phenylsulfonyl)nitrile oxide to acrolein dimethylacetal gave the isoxazole 3. Nucleophilic displacement of the phenylsulfonyl moiety followed by reductive N-O bond cleavage gave the amidine acetal 6.

AB - Regioselective 1,3-dipolar cycloaddition of (phenylsulfonyl)nitrile oxide to acrolein dimethylacetal gave the isoxazole 3. Nucleophilic displacement of the phenylsulfonyl moiety followed by reductive N-O bond cleavage gave the amidine acetal 6.

UR - https://www.scopus.com/pages/publications/84973039763

U2 - 10.1080/00397918908052621

DO - 10.1080/00397918908052621

M3 - Article

AN - SCOPUS:84973039763

SN - 0039-7911

VL - 19

SP - 2237

EP - 2242

JO - Synthetic Communications

JF - Synthetic Communications

IS - 13-14

ER -

The synthesis of amidine acetals as intermediates for the preparation of naturally occurring cyclic amidine antibiotics

Abstract

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