The Protein Ontology: A structured representation of protein forms and complexes

Darren A. Natale; Cecilia N. Arighi; Winona C. Barker; Judith A. Blake; Carol J. Bult; Michael Caudy; Harold J. Drabkin; Peter D'Eustachio; Alexei V. Evsikov; Hongzhan Huang; Jules Nchoutmboube; Natalia V. Roberts; Barry Smith; Jian Zhang; Cathy H. Wu

doi:10.1093/nar/gkq907

The Protein Ontology: A structured representation of protein forms and complexes

Darren A. Natale
, Cecilia N. Arighi
, Winona C. Barker
, Judith A. Blake
, Carol J. Bult
, Michael Caudy
, Harold J. Drabkin
, Peter D'Eustachio
, Alexei V. Evsikov
, Hongzhan Huang
, Jules Nchoutmboube
, Natalia V. Roberts
, Barry Smith
, Jian Zhang
, Cathy H. Wu

Philosophy

Georgetown University
University of Delaware
Jackson Laboratory
Ontario Institute for Cancer Research
New York University

Research output: Contribution to journal › Article › peer-review

117 Scopus citations

Abstract

The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate representations of precise protein forms so as to enhance accessibility to results of protein research. PRO (http://pir .georgetown.edu/pro) is part of the Open Biomedical Ontology Foundry.

Original language	English
Pages (from-to)	D539-D545
Journal	Nucleic Acids Research
Volume	39
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1093/nar/gkq907
State	Published - Jan 2011

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Natale, D. A., Arighi, C. N., Barker, W. C., Blake, J. A., Bult, C. J., Caudy, M., Drabkin, H. J., D'Eustachio, P., Evsikov, A. V., Huang, H., Nchoutmboube, J., Roberts, N. V., Smith, B., Zhang, J., & Wu, C. H. (2011). The Protein Ontology: A structured representation of protein forms and complexes. Nucleic Acids Research, 39(SUPPL. 1), D539-D545. https://doi.org/10.1093/nar/gkq907

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title = "The Protein Ontology: A structured representation of protein forms and complexes",

abstract = "The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate representations of precise protein forms so as to enhance accessibility to results of protein research. PRO (http://pir .georgetown.edu/pro) is part of the Open Biomedical Ontology Foundry.",

author = "Natale, \{Darren A.\} and Arighi, \{Cecilia N.\} and Barker, \{Winona C.\} and Blake, \{Judith A.\} and Bult, \{Carol J.\} and Michael Caudy and Drabkin, \{Harold J.\} and Peter D'Eustachio and Evsikov, \{Alexei V.\} and Hongzhan Huang and Jules Nchoutmboube and Roberts, \{Natalia V.\} and Barry Smith and Jian Zhang and Wu, \{Cathy H.\}",

year = "2011",

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AU - Bult, Carol J.

AU - Caudy, Michael

AU - Drabkin, Harold J.

AU - D'Eustachio, Peter

AU - Evsikov, Alexei V.

AU - Huang, Hongzhan

AU - Nchoutmboube, Jules

AU - Roberts, Natalia V.

AU - Smith, Barry

AU - Zhang, Jian

AU - Wu, Cathy H.

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The Protein Ontology: A structured representation of protein forms and complexes

Abstract

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