The metyrapone test in affective disorders and schizophrenia

G. A. Fava; S. W. Carson; G. I. Perini; M. A. Morphy; G. Molnar; W. J. Jusko

doi:10.1016/S0165-0327(84)80002-6

The metyrapone test in affective disorders and schizophrenia

G. A. Fava
, S. W. Carson
, G. I. Perini
, M. A. Morphy
, G. Molnar
, W. J. Jusko

Pharmaceutical Sciences

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The metyrapone test was applied to patients suffering from major depressive illness with melancholia, from mania, and from schizophrenia. Hypoactivity of the HPA axis as assessed by the test appears to occur infrequently in affective disorders and schizophrenia. High normal or exaggerated responses to metyrapone, as observed in Cushing's disease, appear to be correlated to DST non-suppression in melancholia.

Original language	English
Pages (from-to)	241-247
Number of pages	7
Journal	Journal of Affective Disorders
Volume	6
Issue number	3-4
DOIs	https://doi.org/10.1016/S0165-0327(84)80002-6
State	Published - Jun 1984

Keywords

Affective disorders
Cushing disease
Dexamethasone Suppression Test (DST)
Metyrapone Test
Schizophrenia

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10.1016/S0165-0327(84)80002-6

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abstract = "The metyrapone test was applied to patients suffering from major depressive illness with melancholia, from mania, and from schizophrenia. Hypoactivity of the HPA axis as assessed by the test appears to occur infrequently in affective disorders and schizophrenia. High normal or exaggerated responses to metyrapone, as observed in Cushing's disease, appear to be correlated to DST non-suppression in melancholia.",

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AU - Carson, S. W.

AU - Perini, G. I.

AU - Morphy, M. A.

AU - Molnar, G.

AU - Jusko, W. J.

PY - 1984/6

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AB - The metyrapone test was applied to patients suffering from major depressive illness with melancholia, from mania, and from schizophrenia. Hypoactivity of the HPA axis as assessed by the test appears to occur infrequently in affective disorders and schizophrenia. High normal or exaggerated responses to metyrapone, as observed in Cushing's disease, appear to be correlated to DST non-suppression in melancholia.

KW - Affective disorders

KW - Cushing disease

KW - Dexamethasone Suppression Test (DST)

KW - Metyrapone Test

KW - Schizophrenia

UR - https://www.scopus.com/pages/publications/0021183472

U2 - 10.1016/S0165-0327(84)80002-6

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JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

IS - 3-4

ER -

The metyrapone test in affective disorders and schizophrenia

Abstract

Keywords

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