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The “Great Debate” at Melanoma Bridge 2020: December, 5th, 2020

  • Paolo A. Ascierto
  • , Michael B. Atkins
  • , Alexander M. Eggermont
  • , Jeffrey E. Gershenwald
  • , Jean Jacques Grob
  • , Omid Hamid
  • , Vernon K. Sondak
  • , Jeffrey A. Sosman
  • , Hussein A. Tawbi
  • , Jeffrey S. Weber
  • , Corrado Caracò
  • , Iman Osman
  • , Igor Puzanov
  • IRCCS Istituto nazionale tumori Fondazione Giovanni Pascale - Napoli
  • Georgetown University
  • Utrecht University
  • University of Texas MD Anderson Cancer Center
  • Aix-Marseille Université
  • The Angeles Clinic and Research Institute
  • Moffitt Cancer Center
  • University of South Florida
  • Northwestern University
  • New York University

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The Great Debate session at the 2020 Melanoma Bridge virtual congress (December 3rd–5th, Italy) featured counterpoint views from experts on five specific controversial issues in melanoma. The debates considered whether or not innate immunity is important in the response to cancer and immunotherapy, how useful are the revised American Joint Committee on Cancer (AJCC) classification for the staging of patients, the use of sentinel node biopsy for staging patients, the use of triplet combination of targeted therapy plus immunotherapy versus combined immunotherapy, and the respective benefits of neoadjuvant versus adjuvant therapy. As is usual with Bridge congresses, the debates were assigned by meeting Chairs and positions taken by experts during the debates may not have necessarily reflected their own personal opinion.

Original languageEnglish
Article number142
JournalJournal of Translational Medicine
Volume19
Issue number1
DOIs
StatePublished - Dec 2021

Keywords

  • Adjuvant
  • Anti-CTLA-4
  • Anti-PD-1
  • BRAF inhibitor
  • Immunotherapy
  • MEK inhibitor
  • Melanoma
  • Neoadjuvant
  • Staging
  • Targeted therapy

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