The “Great Debate” at Immunotherapy Bridge 2022, Naples, November 30th–December 1st, 2022

Paolo A. Ascierto; Renier Brentjens; Samir N. Khleif; Kunle Odunsi; Katayoun Rezvani; Marco Ruella; Ryan J. Sullivan; Bernard A. Fox; Igor Puzanov

doi:10.1186/s12967-023-04117-3

The “Great Debate” at Immunotherapy Bridge 2022, Naples, November 30th–December 1st, 2022

Paolo A. Ascierto
, Renier Brentjens
, Samir N. Khleif
, Kunle Odunsi
, Katayoun Rezvani
, Marco Ruella
, Ryan J. Sullivan
, Bernard A. Fox
, Igor Puzanov

Medicine

IRCCS Istituto nazionale tumori Fondazione Giovanni Pascale - Napoli
Roswell Park Cancer Institute
Georgetown University
The University of Chicago
University of Texas MD Anderson Cancer Center
University of Pennsylvania
Massachusetts General Hospital Cancer Center
Robert W. Franz Cancer Research Center

Research output: Contribution to journal › Article › peer-review

Abstract

The 2022 Immunotherapy Bridge congress (November 30–December 1, Naples, Italy) featured a Great Debate session which addressed three contemporary topics in the field of immunotherapy. The debates included counterpoint views from leading experts and considered whether adoptive cell therapy (ACT) has a role in the treatment of solid tumors, the use of peripheral/blood biomarkers versus tumor microenvironment biomarkers for cancer immunotherapy and the role of chimeric antigen receptor T cell versus natural killer cell therapy. As is the tradition in the Immunotherapy Bridge Great Debates, speakers are invited by the meeting Chairs to express one side of the assigned debate and the opinions given may not fully reflect their own personal views. Audiences voted in favour of either side of the topic both before and after each debate.

Original language	English
Article number	275
Journal	Journal of Translational Medicine
Volume	21
Issue number	1
DOIs	https://doi.org/10.1186/s12967-023-04117-3
State	Published - Dec 2023

Keywords

Adoptive cell therapy
Biomarkers
CAR therapy
Cancer
Immunotherapy

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10.1186/s12967-023-04117-3

Cite this

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title = "The “Great Debate” at Immunotherapy Bridge 2022, Naples, November 30th–December 1st, 2022",

abstract = "The 2022 Immunotherapy Bridge congress (November 30–December 1, Naples, Italy) featured a Great Debate session which addressed three contemporary topics in the field of immunotherapy. The debates included counterpoint views from leading experts and considered whether adoptive cell therapy (ACT) has a role in the treatment of solid tumors, the use of peripheral/blood biomarkers versus tumor microenvironment biomarkers for cancer immunotherapy and the role of chimeric antigen receptor T cell versus natural killer cell therapy. As is the tradition in the Immunotherapy Bridge Great Debates, speakers are invited by the meeting Chairs to express one side of the assigned debate and the opinions given may not fully reflect their own personal views. Audiences voted in favour of either side of the topic both before and after each debate.",

keywords = "Adoptive cell therapy, Biomarkers, CAR therapy, Cancer, Immunotherapy",

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AU - Ascierto, Paolo A.

AU - Brentjens, Renier

AU - Khleif, Samir N.

AU - Odunsi, Kunle

AU - Rezvani, Katayoun

AU - Ruella, Marco

AU - Sullivan, Ryan J.

AU - Fox, Bernard A.

AU - Puzanov, Igor

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AB - The 2022 Immunotherapy Bridge congress (November 30–December 1, Naples, Italy) featured a Great Debate session which addressed three contemporary topics in the field of immunotherapy. The debates included counterpoint views from leading experts and considered whether adoptive cell therapy (ACT) has a role in the treatment of solid tumors, the use of peripheral/blood biomarkers versus tumor microenvironment biomarkers for cancer immunotherapy and the role of chimeric antigen receptor T cell versus natural killer cell therapy. As is the tradition in the Immunotherapy Bridge Great Debates, speakers are invited by the meeting Chairs to express one side of the assigned debate and the opinions given may not fully reflect their own personal views. Audiences voted in favour of either side of the topic both before and after each debate.

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KW - Biomarkers

KW - CAR therapy

KW - Cancer

KW - Immunotherapy

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The “Great Debate” at Immunotherapy Bridge 2022, Naples, November 30th–December 1st, 2022

Abstract

Keywords

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