@inproceedings{c699e1cde46645a2a117ba10d0e846c2,
title = "The effect of MSC phenotype on osteogenesis and vasculogenesis in engineered multiphase microenvironments",
abstract = "Statement of Purpose: The inability to create functional vasculature has hampered the clinical application of bone tissue engineering strategies. Cell-based therapies using mesenchymal stromal cells (MSC) have shown potential in enhancing bone formation and neo-vascularization1. However, it is challenging to harness these attributes due to inherent difficulties in directing and maintaining MSC phenotypes with the potential to promote vasculogenesis and osteogenesis. Hence there is a need for improved tissue engineering strategies that utilize their dual potential. In this study we analyzed the temporal plasticity of MSC under osteogenic (OST) and vasculogenic (VAS) stimulation with the long-term goal of developing a multiphasic cell-based therapy for bone regeneration.",
author = "Schott, \{Nicholas G.\} and Annamalai, \{Ramkumar T.\} and Juliar, \{Benjamin A.\} and Stegemann, \{Jan P.\}",
note = "Publisher Copyright: {\textcopyright} 2019 Omnipress - All rights reserved.; 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence ; Conference date: 03-04-2019 Through 06-04-2019",
year = "2019",
language = "English",
series = "Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium",
publisher = "Society for Biomaterials",
pages = "131",
booktitle = "Society for Biomaterials Annual Meeting and Exposition 2019",
}