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The Effect of Antidepressants on Withdrawal in Patients with Alcohol Dependence: A Retrospective Study

  • SUNY Buffalo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The use of electronic health records has expanded in the past decades, with healthcare entities storing terabytes of patient health data. In this study, we investigated how these databases can be utilized to generate clinically relevant information. We used the Office of Addiction Services and Supports Client Data Systems data merged with the NYS Medicaid Data Warehouse to study the relationship of certain antidepressants on alcohol withdrawal (AW) rates in patients with alcohol dependence (AD). We found that in patients with AD, bupropion was associated with a significantly reduced rate of AW compared to selective serotonin reuptake inhibitors (SSRIs). This may be due to the ability of bupropion to inhibit dopaminergic reuptake. This retrospective study provides the advantage of being faster and less expensive than randomized controlled trials (RCTs).

Original languageEnglish
Title of host publicationDigital Health and Informatics Innovations for Sustainable Health Care Systems - Proceedings of MIE 2024
EditorsJohn Mantas, Arie Hasman, George Demiris, Kaija Saranto, Michael Marschollek, Theodoros N. Arvanitis, Ivana Ognjanovic, Arriel Benis, Parisis Gallos, Emmanouil Zoulias, Elisavet Andrikopoulou
PublisherIOS Press BV
Pages284-285
Number of pages2
ISBN (Electronic)9781643685335
DOIs
StatePublished - Aug 22 2024
Event34th Medical Informatics Europe Conference, MIE 2024 - Athens, Greece
Duration: Aug 25 2024Aug 29 2024

Publication series

NameStudies in Health Technology and Informatics
Volume316
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference34th Medical Informatics Europe Conference, MIE 2024
Country/TerritoryGreece
CityAthens
Period08/25/2408/29/24

Keywords

  • Bioinformatics
  • Computational Biology
  • Electronic Health Record

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