The B-alkyl suzuki-miyaura cross-coupling reaction: Development, mechanistic study, and applications in natural product synthesis

Sherry R. Chemler; Dirk Trauner; Samuel J. Danishefsky

doi:10.1002/1521-3773(20011217)40:24<4544::AID-ANIE4544>3.0.CO;2-N

The B-alkyl suzuki-miyaura cross-coupling reaction: Development, mechanistic study, and applications in natural product synthesis

Sherry R. Chemler
, Dirk Trauner
, Samuel J. Danishefsky

Chemistry

University of California at Berkeley
Memorial Sloan-Kettering Cancer Center
Columbia University

Research output: Contribution to journal › Review article › peer-review

899 Scopus citations

Abstract

The development of new reactions that facilitate the creative and efficient synthesis of molecular structures with desirable properties continues to fascinate chemists. The test of a significant contribution is its acceptance over time by the scientific community. The B-alkyl Suzuki-Miyaura crosscoupling reaction appears to be one such reaction. Since its disclosure by Suzuki and Miyaura in 1986, this reaction has been an attractive solution to challenging synthetic problems.

Original language	English
Pages (from-to)	4544-4568
Number of pages	25
Journal	Angewandte Chemie - International Edition
Volume	40
Issue number	24
DOIs	https://doi.org/10.1002/1521-3773(20011217)40:24<4544::AID-ANIE4544>3.0.CO;2-N
State	Published - Dec 17 2001

Keywords

Boranes
C-C coupling
Cross-coupling
Suzuki-Miyaura coupling
Synthetic methods

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10.1002/1521-3773(20011217)40:24<4544::AID-ANIE4544>3.0.CO;2-N

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abstract = "The development of new reactions that facilitate the creative and efficient synthesis of molecular structures with desirable properties continues to fascinate chemists. The test of a significant contribution is its acceptance over time by the scientific community. The B-alkyl Suzuki-Miyaura crosscoupling reaction appears to be one such reaction. Since its disclosure by Suzuki and Miyaura in 1986, this reaction has been an attractive solution to challenging synthetic problems.",

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AU - Danishefsky, Samuel J.

PY - 2001/12/17

Y1 - 2001/12/17

N2 - The development of new reactions that facilitate the creative and efficient synthesis of molecular structures with desirable properties continues to fascinate chemists. The test of a significant contribution is its acceptance over time by the scientific community. The B-alkyl Suzuki-Miyaura crosscoupling reaction appears to be one such reaction. Since its disclosure by Suzuki and Miyaura in 1986, this reaction has been an attractive solution to challenging synthetic problems.

AB - The development of new reactions that facilitate the creative and efficient synthesis of molecular structures with desirable properties continues to fascinate chemists. The test of a significant contribution is its acceptance over time by the scientific community. The B-alkyl Suzuki-Miyaura crosscoupling reaction appears to be one such reaction. Since its disclosure by Suzuki and Miyaura in 1986, this reaction has been an attractive solution to challenging synthetic problems.

KW - Boranes

KW - C-C coupling

KW - Cross-coupling

KW - Suzuki-Miyaura coupling

KW - Synthetic methods

UR - https://www.scopus.com/pages/publications/0035905441

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DO - 10.1002/1521-3773(20011217)40:24<4544::AID-ANIE4544>3.0.CO;2-N

M3 - Review article

AN - SCOPUS:0035905441

SN - 1433-7851

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 24

ER -

The B-alkyl suzuki-miyaura cross-coupling reaction: Development, mechanistic study, and applications in natural product synthesis

Abstract

Keywords

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