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Targeted nanomaterials for phototherapy

  • SUNY Buffalo

Research output: Contribution to journalReview articlepeer-review

157 Scopus citations

Abstract

Phototherapies involve the irradiation of target tissues with light. To further enhance selectivity and potency, numerous molecularly targeted photosensitizers and photoactive nanoparticles have been developed. Active targeting typically involves harnessing the affinity between a ligand and a cell surface receptor for improved accumulation in the targeted tissue. Targeting ligands including peptides, proteins, aptamers and small molecules have been explored for phototherapy. In this review, recent examples of targeted nanomaterials used in phototherapy are summarized.

Original languageEnglish
Pages (from-to)38-58
Number of pages21
JournalNanotheranostics
Volume1
Issue number1
DOIs
StatePublished - 2017

Keywords

  • Cancer
  • Photodynamic therapy
  • Photosensitizers
  • Photothermal therapy
  • Targeting

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