Synthesis of a novel antiretroviral thymidine analog: 1-(2-deoxy-β-d-ribofuranosyl)-4-acetylimidazolin-2-one (imidine)

Xiang Jun Jiang; Thomas I. Kalman

doi:10.1080/15257779408013248

Synthesis of a novel antiretroviral thymidine analog: 1-(2-deoxy-β-d-ribofuranosyl)-4-acetylimidazolin-2-one (imidine)

Xiang Jun Jiang
, Thomas I. Kalman

Chemistry

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The total synthesis of imidine (8), a novel isomer of thymidine is described. Depending on the coupling method used, either the anomeric mixture of the protected desired nucleoside, or the positional isomer 14 is obtained.

Original language	English
Pages (from-to)	379-388
Number of pages	10
Journal	Nucleosides and Nucleotides
Volume	13
Issue number	1-3
DOIs	https://doi.org/10.1080/15257779408013248
State	Published - Mar 1 1994

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title = "Synthesis of a novel antiretroviral thymidine analog: 1-(2-deoxy-β-d-ribofuranosyl)-4-acetylimidazolin-2-one (imidine)",

abstract = "The total synthesis of imidine (8), a novel isomer of thymidine is described. Depending on the coupling method used, either the anomeric mixture of the protected desired nucleoside, or the positional isomer 14 is obtained.",

author = "Jiang, \{Xiang Jun\} and Kalman, \{Thomas I.\}",

year = "1994",

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T1 - Synthesis of a novel antiretroviral thymidine analog

T2 - 1-(2-deoxy-β-d-ribofuranosyl)-4-acetylimidazolin-2-one (imidine)

AU - Jiang, Xiang Jun

AU - Kalman, Thomas I.

PY - 1994/3/1

Y1 - 1994/3/1

N2 - The total synthesis of imidine (8), a novel isomer of thymidine is described. Depending on the coupling method used, either the anomeric mixture of the protected desired nucleoside, or the positional isomer 14 is obtained.

AB - The total synthesis of imidine (8), a novel isomer of thymidine is described. Depending on the coupling method used, either the anomeric mixture of the protected desired nucleoside, or the positional isomer 14 is obtained.

UR - https://www.scopus.com/pages/publications/0028331855

U2 - 10.1080/15257779408013248

DO - 10.1080/15257779408013248

M3 - Article

AN - SCOPUS:0028331855

SN - 0732-8311

VL - 13

SP - 379

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JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

IS - 1-3

ER -

Synthesis of a novel antiretroviral thymidine analog: 1-(2-deoxy-β-d-ribofuranosyl)-4-acetylimidazolin-2-one (imidine)

Abstract

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