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Synthesis of 4‐(2‐chloroethyl)‐2,3‐dihydro[1,4]oxazino[2,3‐b]quinoline and 4‐(2‐chloroethyl)2,3‐dihydropyrido[2,3‐b][1,4]oxazine

  • SUNY Buffalo

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Abstract

The title compounds were synthesized from 3‐[bis(2‐hydroxyethyl)amino]quinolin‐2(1H)‐one 11a and 3‐[bis(2‐hydroxyethyl)amino]pyridin‐2(1H)‐one 18 respectively. The preparation involved a tandem chlorination/cyclization reaction.

Original languageEnglish
Pages (from-to)1533-1536
Number of pages4
JournalJournal of Heterocyclic Chemistry
Volume30
Issue number6
DOIs
StatePublished - Dec 1993

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