Synthesis and biological significance of porphyrin-based photosensitizers in photodynamic therapy

Penny Joshi; Ravindra K. Pandey

doi:10.1201/b17288

Synthesis and biological significance of porphyrin-based photosensitizers in photodynamic therapy

Penny Joshi
, Ravindra K. Pandey

Institute for Lasers Photonics and Biophotonics

Roswell Park Cancer Institute

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

PDT is a promising cancer treatment that involves the combination of visible light and a photosensitizer.4 Each factor is harmless by itself, but when combined with oxygen, they can produce lethal cytotoxic agents, initially singlet oxygen, that inactivate the tumor cells.5 is enables greater selectivity.

Original language	English
Title of host publication	Biomedical Photonics Handbook, Second Edition
Subtitle of host publication	Therapeutics and Advanced Biophotonics
Publisher	CRC Press
Pages	31-65
Number of pages	35
ISBN (Electronic)	9781420085174
ISBN (Print)	9781420085167
DOIs	https://doi.org/10.1201/b17288
State	Published - Jan 1 2014

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abstract = "PDT is a promising cancer treatment that involves the combination of visible light and a photosensitizer.4 Each factor is harmless by itself, but when combined with oxygen, they can produce lethal cytotoxic agents, initially singlet oxygen, that inactivate the tumor cells.5 is enables greater selectivity.",

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Synthesis and biological significance of porphyrin-based photosensitizers in photodynamic therapy

Abstract

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