Synthesis and Antileukemic Activity of 1-Methyl-2, 5-Diphenyl-3, 4-Bis(Hydroxymethyl)-, 1, 2, 3-Triphenyl-4, 5-Bis(Hydroxymethyl)-, and 1-Methyl-2, 3-Diphenyl-4, 5-Bis(Hydroxymethyl)Pyrrole Bis(N-Methylcarbamate)

Wayne K. Anderson; Michael J. Halat; Arvela C. Rick

doi:10.1021/jm00175a018

Synthesis and Antileukemic Activity of 1-Methyl-2, 5-Diphenyl-3, 4-Bis(Hydroxymethyl)-, 1, 2, 3-Triphenyl-4, 5-Bis(Hydroxymethyl)-, and 1-Methyl-2, 3-Diphenyl-4, 5-Bis(Hydroxymethyl)Pyrrole Bis(N-Methylcarbamate)

Wayne K. Anderson
, Michael J. Halat
, Arvela C. Rick

Pharmaceutical Sciences

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

The syntheses for the bisiN-methylcarbamates) 3, 4a, 4b, ana 5 are described. All four compounds were active in the in vivo P388 lymphocytic leukemia assay, with 3 being the most active.

Original language	English
Pages (from-to)	87-89
Number of pages	3
Journal	Journal of Medicinal Chemistry
Volume	23
Issue number	1
DOIs	https://doi.org/10.1021/jm00175a018
State	Published - Jan 1 1980

Access to Document

10.1021/jm00175a018

Fingerprint

Dive into the research topics of 'Synthesis and Antileukemic Activity of 1-Methyl-2, 5-Diphenyl-3, 4-Bis(Hydroxymethyl)-, 1, 2, 3-Triphenyl-4, 5-Bis(Hydroxymethyl)-, and 1-Methyl-2, 3-Diphenyl-4, 5-Bis(Hydroxymethyl)Pyrrole Bis(N-Methylcarbamate)'. Together they form a unique fingerprint.

Cite this

@article{d46c7f50471e4d0484107be0a1a23664,

title = "Synthesis and Antileukemic Activity of 1-Methyl-2, 5-Diphenyl-3, 4-Bis(Hydroxymethyl)-, 1, 2, 3-Triphenyl-4, 5-Bis(Hydroxymethyl)-, and 1-Methyl-2, 3-Diphenyl-4, 5-Bis(Hydroxymethyl)Pyrrole Bis(N-Methylcarbamate)",

abstract = "The syntheses for the bisiN-methylcarbamates) 3, 4a, 4b, ana 5 are described. All four compounds were active in the in vivo P388 lymphocytic leukemia assay, with 3 being the most active.",

author = "Anderson, \{Wayne K.\} and Halat, \{Michael J.\} and Rick, \{Arvela C.\}",

year = "1980",

month = jan,

day = "1",

doi = "10.1021/jm00175a018",

language = "English",

volume = "23",

pages = "87--89",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "1",

}

Synthesis and Antileukemic Activity of 1-Methyl-2, 5-Diphenyl-3, 4-Bis(Hydroxymethyl)-, 1, 2, 3-Triphenyl-4, 5-Bis(Hydroxymethyl)-, and 1-Methyl-2, 3-Diphenyl-4, 5-Bis(Hydroxymethyl)Pyrrole Bis(N-Methylcarbamate). / Anderson, Wayne K.; Halat, Michael J.; Rick, Arvela C.
In: Journal of Medicinal Chemistry, Vol. 23, No. 1, 01.01.1980, p. 87-89.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Synthesis and Antileukemic Activity of 1-Methyl-2, 5-Diphenyl-3, 4-Bis(Hydroxymethyl)-, 1, 2, 3-Triphenyl-4, 5-Bis(Hydroxymethyl)-, and 1-Methyl-2, 3-Diphenyl-4, 5-Bis(Hydroxymethyl)Pyrrole Bis(N-Methylcarbamate)

AU - Anderson, Wayne K.

AU - Halat, Michael J.

AU - Rick, Arvela C.

PY - 1980/1/1

Y1 - 1980/1/1

N2 - The syntheses for the bisiN-methylcarbamates) 3, 4a, 4b, ana 5 are described. All four compounds were active in the in vivo P388 lymphocytic leukemia assay, with 3 being the most active.

AB - The syntheses for the bisiN-methylcarbamates) 3, 4a, 4b, ana 5 are described. All four compounds were active in the in vivo P388 lymphocytic leukemia assay, with 3 being the most active.

UR - https://www.scopus.com/pages/publications/0018837074

U2 - 10.1021/jm00175a018

DO - 10.1021/jm00175a018

M3 - Article

C2 - 7359518

AN - SCOPUS:0018837074

SN - 0022-2623

VL - 23

SP - 87

EP - 89

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 1

ER -

Synthesis and Antileukemic Activity of 1-Methyl-2, 5-Diphenyl-3, 4-Bis(Hydroxymethyl)-, 1, 2, 3-Triphenyl-4, 5-Bis(Hydroxymethyl)-, and 1-Methyl-2, 3-Diphenyl-4, 5-Bis(Hydroxymethyl)Pyrrole Bis(N-Methylcarbamate)

Abstract

Access to Document

Other files and links

Fingerprint

Cite this