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Synthesis and antibody binding properties of glycodendrimers bearing the tumor related T-antigen

  • University of Ottawa

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

Breast cancer marker T-antigen (Gal(β1-3)αGalNAc) was prepared as an allyl glycoside that was transformed into an active ester and coupled to a series of poly(amidoamine) dendrimers showing strong binding to mouse monoclonal IgG antibodies and serving as useful coating antigens in microtiter plates.

Original languageEnglish
Pages (from-to)257-258
Number of pages2
JournalChemical Communications
Issue number3
DOIs
StatePublished - Feb 7 2001

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