Synthesis and Absolute Configuration of New Trichloro Steroids with Cyclopropane‐Containing Side Chains

Robert W. Lang; Carl Djerassi; Phyllis D. Strong; Dale C. Swenson; William L. Duax

doi:10.1002/hlca.19810640847

Synthesis and Absolute Configuration of New Trichloro Steroids with Cyclopropane‐Containing Side Chains

Robert W. Lang
, Carl Djerassi
, Phyllis D. Strong
, Dale C. Swenson
, William L. Duax

Department of Structural Biology

Stanford University
Hauptman-Woodward Medical Research Institute, Inc.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The determination of the absolute configuration of the trichloro steroids 2a and 2c cf. Scheme 1 by means of two X‐ray crystal structure analyses is reported and applies also to the determination of the absolute configurations of several derived steroidal cyclopropanes [1]. The preparation of the chlorinated derivatives 2a‐c is described and the spectroscopic properties of 1 and 2 are summarized.

Original language	English
Pages (from-to)	2853-2859
Number of pages	7
Journal	Helvetica Chimica Acta
Volume	64
Issue number	8
DOIs	https://doi.org/10.1002/hlca.19810640847
State	Published - Dec 16 1981

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title = "Synthesis and Absolute Configuration of New Trichloro Steroids with Cyclopropane‐Containing Side Chains",

abstract = "The determination of the absolute configuration of the trichloro steroids 2a and 2c cf. Scheme 1 by means of two X‐ray crystal structure analyses is reported and applies also to the determination of the absolute configurations of several derived steroidal cyclopropanes [1]. The preparation of the chlorinated derivatives 2a‐c is described and the spectroscopic properties of 1 and 2 are summarized.",

author = "Lang, \{Robert W.\} and Carl Djerassi and Strong, \{Phyllis D.\} and Swenson, \{Dale C.\} and Duax, \{William L.\}",

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T1 - Synthesis and Absolute Configuration of New Trichloro Steroids with Cyclopropane‐Containing Side Chains

AU - Lang, Robert W.

AU - Djerassi, Carl

AU - Strong, Phyllis D.

AU - Swenson, Dale C.

AU - Duax, William L.

PY - 1981/12/16

Y1 - 1981/12/16

N2 - The determination of the absolute configuration of the trichloro steroids 2a and 2c cf. Scheme 1 by means of two X‐ray crystal structure analyses is reported and applies also to the determination of the absolute configurations of several derived steroidal cyclopropanes [1]. The preparation of the chlorinated derivatives 2a‐c is described and the spectroscopic properties of 1 and 2 are summarized.

AB - The determination of the absolute configuration of the trichloro steroids 2a and 2c cf. Scheme 1 by means of two X‐ray crystal structure analyses is reported and applies also to the determination of the absolute configurations of several derived steroidal cyclopropanes [1]. The preparation of the chlorinated derivatives 2a‐c is described and the spectroscopic properties of 1 and 2 are summarized.

UR - https://www.scopus.com/pages/publications/0345303407

U2 - 10.1002/hlca.19810640847

DO - 10.1002/hlca.19810640847

M3 - Article

AN - SCOPUS:0345303407

SN - 0018-019X

VL - 64

SP - 2853

EP - 2859

JO - Helvetica Chimica Acta

JF - Helvetica Chimica Acta

IS - 8

ER -

Synthesis and Absolute Configuration of New Trichloro Steroids with Cyclopropane‐Containing Side Chains

Abstract

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