Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper)

Ravindra K. Pandey; M. G. Vicente; Fuu Yau Shiau; Thomas J. Dougherty; Kevin M. Smith

Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper)

Ravindra K. Pandey
, M. G. Vicente
, Fuu Yau Shiau
, Thomas J. Dougherty
, Kevin M. Smith

Institute for Lasers Photonics and Biophotonics

University of California at Davis

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

5 Scopus citations

Abstract

Efficient methods for the syntheses of porphyrin and chlorin dimers joined with variable length carbon units, either at meso positions or at β-pyrrolic positions, are described. The in vivo testing results for some of the dimers are also discussed. The main objective of this work is to understand the structure/activity relationships among carbon-carbon linked dimers of porphyrins and chlorins. It is anticipated that this study will assist the authors in designing photosensitizers with required chemical and photochemical properties.

Original language	English
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Publisher	Publ by Int Soc for Optical Engineering
Pages	356-361
Number of pages	6
ISBN (Print)	0819405167
State	Published - 1991
Event	Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques - Los Angeles, CA, USA Duration: Jan 23 1991 → Jan 25 1991

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	1426
ISSN (Print)	0277-786X

Conference

Conference	Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques
City	Los Angeles, CA, USA
Period	01/23/91 → 01/25/91

Cite this

Pandey, R. K., Vicente, M. G., Shiau, F. Y., Dougherty, T. J., & Smith, K. M. (1991). Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper). In Proceedings of SPIE - The International Society for Optical Engineering (pp. 356-361). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1426). Publ by Int Soc for Optical Engineering.

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title = "Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper)",

abstract = "Efficient methods for the syntheses of porphyrin and chlorin dimers joined with variable length carbon units, either at meso positions or at β-pyrrolic positions, are described. The in vivo testing results for some of the dimers are also discussed. The main objective of this work is to understand the structure/activity relationships among carbon-carbon linked dimers of porphyrins and chlorins. It is anticipated that this study will assist the authors in designing photosensitizers with required chemical and photochemical properties.",

author = "Pandey, \{Ravindra K.\} and Vicente, \{M. G.\} and Shiau, \{Fuu Yau\} and Dougherty, \{Thomas J.\} and Smith, \{Kevin M.\}",

year = "1991",

language = "English",

isbn = "0819405167",

series = "Proceedings of SPIE - The International Society for Optical Engineering",

publisher = "Publ by Int Soc for Optical Engineering",

pages = "356--361",

booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

note = "Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques ; Conference date: 23-01-1991 Through 25-01-1991",

}

Pandey, RK, Vicente, MG, Shiau, FY, Dougherty, TJ & Smith, KM 1991, Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper). in Proceedings of SPIE - The International Society for Optical Engineering. Proceedings of SPIE - The International Society for Optical Engineering, vol. 1426, Publ by Int Soc for Optical Engineering, pp. 356-361, Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques, Los Angeles, CA, USA, 01/23/91.

Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper). / Pandey, Ravindra K.; Vicente, M. G.; Shiau, Fuu Yau et al.
Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, 1991. p. 356-361 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1426).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper)

AU - Pandey, Ravindra K.

AU - Vicente, M. G.

AU - Shiau, Fuu Yau

AU - Dougherty, Thomas J.

AU - Smith, Kevin M.

PY - 1991

Y1 - 1991

N2 - Efficient methods for the syntheses of porphyrin and chlorin dimers joined with variable length carbon units, either at meso positions or at β-pyrrolic positions, are described. The in vivo testing results for some of the dimers are also discussed. The main objective of this work is to understand the structure/activity relationships among carbon-carbon linked dimers of porphyrins and chlorins. It is anticipated that this study will assist the authors in designing photosensitizers with required chemical and photochemical properties.

AB - Efficient methods for the syntheses of porphyrin and chlorin dimers joined with variable length carbon units, either at meso positions or at β-pyrrolic positions, are described. The in vivo testing results for some of the dimers are also discussed. The main objective of this work is to understand the structure/activity relationships among carbon-carbon linked dimers of porphyrins and chlorins. It is anticipated that this study will assist the authors in designing photosensitizers with required chemical and photochemical properties.

UR - https://www.scopus.com/pages/publications/0025846011

M3 - Conference contribution

AN - SCOPUS:0025846011

SN - 0819405167

T3 - Proceedings of SPIE - The International Society for Optical Engineering

SP - 356

EP - 361

BT - Proceedings of SPIE - The International Society for Optical Engineering

PB - Publ by Int Soc for Optical Engineering

T2 - Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques

Y2 - 23 January 1991 through 25 January 1991

ER -

Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper)

Abstract

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