Syntheses of hematoporphyrin dimers and trimers with ether linkages

Ravindra K. Pandey; Thomas J. Dougherty; Kevin M. Smith

doi:10.1016/S0040-4039(00)80573-0

Syntheses of hematoporphyrin dimers and trimers with ether linkages

Ravindra K. Pandey
, Thomas J. Dougherty
, Kevin M. Smith

Institute for Lasers Photonics and Biophotonics

Roswell Park Cancer Institute
University of California at Davis

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

In order to aid in elucidation of the structure of the active components in hematoporphyrin derivative (Hpd), the first syntheses of an ether-linked hematoporphyrin dimer (6) and trimer (12) are described. After ester hydrolysis, these compounds were positively identified, by comparative HPLC, as components in Photofrin®-II.

Original language	English
Pages (from-to)	4657-4660
Number of pages	4
Journal	Tetrahedron Letters
Volume	29
Issue number	37
DOIs	https://doi.org/10.1016/S0040-4039(00)80573-0
State	Published - 1988

Access to Document

10.1016/S0040-4039(00)80573-0

Cite this

@article{be467e2b21f24c049e83a73f167d54fb,

title = "Syntheses of hematoporphyrin dimers and trimers with ether linkages",

abstract = "In order to aid in elucidation of the structure of the active components in hematoporphyrin derivative (Hpd), the first syntheses of an ether-linked hematoporphyrin dimer (6) and trimer (12) are described. After ester hydrolysis, these compounds were positively identified, by comparative HPLC, as components in Photofrin{\textregistered}-II.",

author = "Pandey, \{Ravindra K.\} and Dougherty, \{Thomas J.\} and Smith, \{Kevin M.\}",

year = "1988",

doi = "10.1016/S0040-4039(00)80573-0",

language = "English",

volume = "29",

pages = "4657--4660",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "37",

}

TY - JOUR

T1 - Syntheses of hematoporphyrin dimers and trimers with ether linkages

AU - Pandey, Ravindra K.

AU - Dougherty, Thomas J.

AU - Smith, Kevin M.

PY - 1988

Y1 - 1988

N2 - In order to aid in elucidation of the structure of the active components in hematoporphyrin derivative (Hpd), the first syntheses of an ether-linked hematoporphyrin dimer (6) and trimer (12) are described. After ester hydrolysis, these compounds were positively identified, by comparative HPLC, as components in Photofrin®-II.

AB - In order to aid in elucidation of the structure of the active components in hematoporphyrin derivative (Hpd), the first syntheses of an ether-linked hematoporphyrin dimer (6) and trimer (12) are described. After ester hydrolysis, these compounds were positively identified, by comparative HPLC, as components in Photofrin®-II.

UR - https://www.scopus.com/pages/publications/0023720088

U2 - 10.1016/S0040-4039(00)80573-0

DO - 10.1016/S0040-4039(00)80573-0

M3 - Article

AN - SCOPUS:0023720088

SN - 0040-4039

VL - 29

SP - 4657

EP - 4660

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 37

ER -

Syntheses of hematoporphyrin dimers and trimers with ether linkages

Abstract

Access to Document

Other files and links

Fingerprint

Cite this