Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy

Andrei N. Kozyrev; Gang Zheng; Elizabeth Lazarou; Thomas J. Dougherty; Kevin M. Smith; Ravindra K. Pandey

doi:10.1016/S0040-4039(97)00621-7

Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy

Andrei N. Kozyrev
, Gang Zheng
, Elizabeth Lazarou
, Thomas J. Dougherty
, Kevin M. Smith
, Ravindra K. Pandey

Institute for Lasers Photonics and Biophotonics

Roswell Park Cancer Institute
University of California at Davis

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Efficient syntheses and mechanisms of the formation of some novel porphyrins and chlorins with cyclic anhydride, imide and isoimide rings bearing various N-substituents as possible target-specific photosensitizers for photodynamic therapy are presented. Porphyrins with such cyclic ring systems are named as 'emeraldins' due to their intense green color. This class of compounds show a unique reverse etio-type absorption spectra.

Original language	English
Pages (from-to)	3335-3338
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	19
DOIs	https://doi.org/10.1016/S0040-4039(97)00621-7
State	Published - May 12 1997

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title = "Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy",

abstract = "Efficient syntheses and mechanisms of the formation of some novel porphyrins and chlorins with cyclic anhydride, imide and isoimide rings bearing various N-substituents as possible target-specific photosensitizers for photodynamic therapy are presented. Porphyrins with such cyclic ring systems are named as 'emeraldins' due to their intense green color. This class of compounds show a unique reverse etio-type absorption spectra.",

author = "Kozyrev, \{Andrei N.\} and Gang Zheng and Elizabeth Lazarou and Dougherty, \{Thomas J.\} and Smith, \{Kevin M.\} and Pandey, \{Ravindra K.\}",

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journal = "Tetrahedron Letters",

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T1 - Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy

AU - Kozyrev, Andrei N.

AU - Zheng, Gang

AU - Lazarou, Elizabeth

AU - Dougherty, Thomas J.

AU - Smith, Kevin M.

AU - Pandey, Ravindra K.

PY - 1997/5/12

Y1 - 1997/5/12

N2 - Efficient syntheses and mechanisms of the formation of some novel porphyrins and chlorins with cyclic anhydride, imide and isoimide rings bearing various N-substituents as possible target-specific photosensitizers for photodynamic therapy are presented. Porphyrins with such cyclic ring systems are named as 'emeraldins' due to their intense green color. This class of compounds show a unique reverse etio-type absorption spectra.

AB - Efficient syntheses and mechanisms of the formation of some novel porphyrins and chlorins with cyclic anhydride, imide and isoimide rings bearing various N-substituents as possible target-specific photosensitizers for photodynamic therapy are presented. Porphyrins with such cyclic ring systems are named as 'emeraldins' due to their intense green color. This class of compounds show a unique reverse etio-type absorption spectra.

UR - https://www.scopus.com/pages/publications/0030970290

U2 - 10.1016/S0040-4039(97)00621-7

DO - 10.1016/S0040-4039(97)00621-7

M3 - Article

AN - SCOPUS:0030970290

SN - 0040-4039

VL - 38

SP - 3335

EP - 3338

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 19

ER -

Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy

Abstract

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