Surface-phase separation of PEO-containing biodegradable PLLA blends and block copolymers

Joo Woon Lee; Euh Duck Jeong; Eun Jeong Cho; Joseph A. Gardella; Wesley Hicks; Robert Hard; Frank V. Bright

doi:10.1016/j.apsusc.2008.07.121

Surface-phase separation of PEO-containing biodegradable PLLA blends and block copolymers

Joo Woon Lee
, Euh Duck Jeong
, Eun Jeong Cho
, Joseph A. Gardella
, Wesley Hicks
, Robert Hard
, Frank V. Bright

Korea National University of Transportation
Korea Basic Science Institute
University of Texas at Austin
Roswell Park Cancer Institute

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The surface chemistry of two series of poly(ethylene oxide) (PEO)-containing biodegradable poly(l-lactic acid) (PLLA) matrix systems has been investigated using time-of-flight SIMS (ToF-SIMS) and XPS. The two systems are (1) PLLA blend matrices with an amphiphilic Pluronic ^® P-104 surfactant, P(EO) ₂₇ -b-P(PO) ₆₁ -b-P(EO) ₂₇ , and (2) PLLA-b-PEO diblock and PLLA-b-PEO-b-PLLA triblock copolymers. The phase separation is analyzed in determining the surface enrichment of the component and chemical composition at the polymer-air interface. The PEO component is surface-dominant in the blend system in contrast to the surface excess of poly(propylene oxide) (PPO) in pure Pluronic ^® P-104. The block copolymer system shows the surface enrichment of PLLA component. These results can be explained in terms of the change in surface free energy for the block copolymers and the better miscibility of PLLA and PPO against amphiphilic PEO for the blends, respectively.

Original language	English
Pages (from-to)	2360-2364
Number of pages	5
Journal	Applied Surface Science
Volume	255
Issue number	5 PART 1
DOIs	https://doi.org/10.1016/j.apsusc.2008.07.121
State	Published - Dec 30 2008

Keywords

Biodegradable
Block copolymer
PEO
PLLA
Secondary ion mass spectrometry
XPS

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10.1016/j.apsusc.2008.07.121

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@article{6bd84fefa3ae49709c9fc8f43910ad3b,

title = "Surface-phase separation of PEO-containing biodegradable PLLA blends and block copolymers",

abstract = " The surface chemistry of two series of poly(ethylene oxide) (PEO)-containing biodegradable poly(l-lactic acid) (PLLA) matrix systems has been investigated using time-of-flight SIMS (ToF-SIMS) and XPS. The two systems are (1) PLLA blend matrices with an amphiphilic Pluronic {\textregistered} P-104 surfactant, P(EO) 27 -b-P(PO) 61 -b-P(EO) 27 , and (2) PLLA-b-PEO diblock and PLLA-b-PEO-b-PLLA triblock copolymers. The phase separation is analyzed in determining the surface enrichment of the component and chemical composition at the polymer-air interface. The PEO component is surface-dominant in the blend system in contrast to the surface excess of poly(propylene oxide) (PPO) in pure Pluronic {\textregistered} P-104. The block copolymer system shows the surface enrichment of PLLA component. These results can be explained in terms of the change in surface free energy for the block copolymers and the better miscibility of PLLA and PPO against amphiphilic PEO for the blends, respectively.",

keywords = "Biodegradable, Block copolymer, PEO, PLLA, Secondary ion mass spectrometry, XPS",

author = "Lee, \{Joo Woon\} and Jeong, \{Euh Duck\} and Cho, \{Eun Jeong\} and Gardella, \{Joseph A.\} and Wesley Hicks and Robert Hard and Bright, \{Frank V.\}",

year = "2008",

month = dec,

day = "30",

doi = "10.1016/j.apsusc.2008.07.121",

language = "English",

volume = "255",

pages = "2360--2364",

journal = "Applied Surface Science",

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publisher = "Elsevier B.V.",

number = "5 PART 1",

}

TY - JOUR

T1 - Surface-phase separation of PEO-containing biodegradable PLLA blends and block copolymers

AU - Lee, Joo Woon

AU - Jeong, Euh Duck

AU - Cho, Eun Jeong

AU - Gardella, Joseph A.

AU - Hicks, Wesley

AU - Hard, Robert

AU - Bright, Frank V.

PY - 2008/12/30

Y1 - 2008/12/30

N2 - The surface chemistry of two series of poly(ethylene oxide) (PEO)-containing biodegradable poly(l-lactic acid) (PLLA) matrix systems has been investigated using time-of-flight SIMS (ToF-SIMS) and XPS. The two systems are (1) PLLA blend matrices with an amphiphilic Pluronic ® P-104 surfactant, P(EO) 27 -b-P(PO) 61 -b-P(EO) 27 , and (2) PLLA-b-PEO diblock and PLLA-b-PEO-b-PLLA triblock copolymers. The phase separation is analyzed in determining the surface enrichment of the component and chemical composition at the polymer-air interface. The PEO component is surface-dominant in the blend system in contrast to the surface excess of poly(propylene oxide) (PPO) in pure Pluronic ® P-104. The block copolymer system shows the surface enrichment of PLLA component. These results can be explained in terms of the change in surface free energy for the block copolymers and the better miscibility of PLLA and PPO against amphiphilic PEO for the blends, respectively.

AB - The surface chemistry of two series of poly(ethylene oxide) (PEO)-containing biodegradable poly(l-lactic acid) (PLLA) matrix systems has been investigated using time-of-flight SIMS (ToF-SIMS) and XPS. The two systems are (1) PLLA blend matrices with an amphiphilic Pluronic ® P-104 surfactant, P(EO) 27 -b-P(PO) 61 -b-P(EO) 27 , and (2) PLLA-b-PEO diblock and PLLA-b-PEO-b-PLLA triblock copolymers. The phase separation is analyzed in determining the surface enrichment of the component and chemical composition at the polymer-air interface. The PEO component is surface-dominant in the blend system in contrast to the surface excess of poly(propylene oxide) (PPO) in pure Pluronic ® P-104. The block copolymer system shows the surface enrichment of PLLA component. These results can be explained in terms of the change in surface free energy for the block copolymers and the better miscibility of PLLA and PPO against amphiphilic PEO for the blends, respectively.

KW - Biodegradable

KW - Block copolymer

KW - PEO

KW - PLLA

KW - Secondary ion mass spectrometry

KW - XPS

UR - https://www.scopus.com/pages/publications/56949098903

U2 - 10.1016/j.apsusc.2008.07.121

DO - 10.1016/j.apsusc.2008.07.121

M3 - Article

AN - SCOPUS:56949098903

SN - 0169-4332

VL - 255

SP - 2360

EP - 2364

JO - Applied Surface Science

JF - Applied Surface Science

IS - 5 PART 1

ER -

Surface-phase separation of PEO-containing biodegradable PLLA blends and block copolymers

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Keywords

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