Study of antiangiogenic agents with possible therapeutic applications in neoplastic disorders and macular degeneration

J. L. Ambrus; C. A. Toumbis; C. P. Karakousis; M. Kulaylat; S. Akhter; L. Plavsic

Study of antiangiogenic agents with possible therapeutic applications in neoplastic disorders and macular degeneration

J. L. Ambrus
, C. A. Toumbis
, C. P. Karakousis
, M. Kulaylat
, S. Akhter
, L. Plavsic

Medicine

Roswell Park Cancer Institute
SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Using a previously developed method (Ambrus, et al., 1991), we found that pentoxifylline and thalidomide potentiate each others antiangiogenic effect induced by human malignant melanoma cells in the cornea of Macaca arctoides monkeys. Pentoxifylline was kindly supplied by Drs. P. Savitsky and B. Cobert from the Hoechst Marion Roussel Pharmaceutical Company. Thalidomide was obtained from commercial sources.

Original language	English
Pages (from-to)	278-282
Number of pages	5
Journal	Journal of Medicine
Volume	31
Issue number	5-6
State	Published - 2000

Keywords

Angiogenesis
Human malignant melanoma
Pentoxifylline
Thalidomide

Cite this

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title = "Study of antiangiogenic agents with possible therapeutic applications in neoplastic disorders and macular degeneration",

abstract = "Using a previously developed method (Ambrus, et al., 1991), we found that pentoxifylline and thalidomide potentiate each others antiangiogenic effect induced by human malignant melanoma cells in the cornea of Macaca arctoides monkeys. Pentoxifylline was kindly supplied by Drs. P. Savitsky and B. Cobert from the Hoechst Marion Roussel Pharmaceutical Company. Thalidomide was obtained from commercial sources.",

keywords = "Angiogenesis, Human malignant melanoma, Pentoxifylline, Thalidomide",

author = "Ambrus, \{J. L.\} and Toumbis, \{C. A.\} and Karakousis, \{C. P.\} and M. Kulaylat and S. Akhter and L. Plavsic",

year = "2000",

language = "English",

volume = "31",

pages = "278--282",

journal = "Journal of Medicine",

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T1 - Study of antiangiogenic agents with possible therapeutic applications in neoplastic disorders and macular degeneration

AU - Ambrus, J. L.

AU - Toumbis, C. A.

AU - Karakousis, C. P.

AU - Kulaylat, M.

AU - Akhter, S.

AU - Plavsic, L.

PY - 2000

Y1 - 2000

N2 - Using a previously developed method (Ambrus, et al., 1991), we found that pentoxifylline and thalidomide potentiate each others antiangiogenic effect induced by human malignant melanoma cells in the cornea of Macaca arctoides monkeys. Pentoxifylline was kindly supplied by Drs. P. Savitsky and B. Cobert from the Hoechst Marion Roussel Pharmaceutical Company. Thalidomide was obtained from commercial sources.

AB - Using a previously developed method (Ambrus, et al., 1991), we found that pentoxifylline and thalidomide potentiate each others antiangiogenic effect induced by human malignant melanoma cells in the cornea of Macaca arctoides monkeys. Pentoxifylline was kindly supplied by Drs. P. Savitsky and B. Cobert from the Hoechst Marion Roussel Pharmaceutical Company. Thalidomide was obtained from commercial sources.

KW - Angiogenesis

KW - Human malignant melanoma

KW - Pentoxifylline

KW - Thalidomide

UR - https://www.scopus.com/pages/publications/0034447850

M3 - Article

C2 - 11508321

AN - SCOPUS:0034447850

SN - 0025-7850

VL - 31

SP - 278

EP - 282

JO - Journal of Medicine

JF - Journal of Medicine

IS - 5-6

ER -

Study of antiangiogenic agents with possible therapeutic applications in neoplastic disorders and macular degeneration

Abstract

Keywords

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