Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development

M. I. Klein; S. Duarte; J. Xiao; S. Mitra; T. H. Foster; H. Koo

doi:10.1128/AEM.01299-08

Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development

M. I. Klein
, S. Duarte
, J. Xiao
, S. Mitra
, T. H. Foster
, H. Koo

Restorative Dentistry Administration

University of Rochester

Research output: Contribution to journal › Article › peer-review

142 Scopus citations

Abstract

The interaction of sucrose and starch with bacterial glucosyltransferases and human salivary amylase may enhance the pathogenic potential of Streptococcus mutatis within biofilms by influencing the structural organization of the extracellular matrix and modulating the expression of genes involved in exopolysaccharide synthesis and specific sugar transport and two-component systems.

Original language	English
Pages (from-to)	837-841
Number of pages	5
Journal	Applied and Environmental Microbiology
Volume	75
Issue number	3
DOIs	https://doi.org/10.1128/AEM.01299-08
State	Published - Feb 2009

Access to Document

10.1128/AEM.01299-08

Cite this

@article{ebe3a711c2334d008082358a1d54cb1b,

title = "Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development",

abstract = "The interaction of sucrose and starch with bacterial glucosyltransferases and human salivary amylase may enhance the pathogenic potential of Streptococcus mutatis within biofilms by influencing the structural organization of the extracellular matrix and modulating the expression of genes involved in exopolysaccharide synthesis and specific sugar transport and two-component systems.",

author = "Klein, \{M. I.\} and S. Duarte and J. Xiao and S. Mitra and Foster, \{T. H.\} and H. Koo",

year = "2009",

month = feb,

doi = "10.1128/AEM.01299-08",

language = "English",

volume = "75",

pages = "837--841",

journal = "Applied and Environmental Microbiology",

issn = "0099-2240",

publisher = "American Society for Microbiology",

number = "3",

}

TY - JOUR

T1 - Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development

AU - Klein, M. I.

AU - Duarte, S.

AU - Xiao, J.

AU - Mitra, S.

AU - Foster, T. H.

AU - Koo, H.

PY - 2009/2

Y1 - 2009/2

N2 - The interaction of sucrose and starch with bacterial glucosyltransferases and human salivary amylase may enhance the pathogenic potential of Streptococcus mutatis within biofilms by influencing the structural organization of the extracellular matrix and modulating the expression of genes involved in exopolysaccharide synthesis and specific sugar transport and two-component systems.

AB - The interaction of sucrose and starch with bacterial glucosyltransferases and human salivary amylase may enhance the pathogenic potential of Streptococcus mutatis within biofilms by influencing the structural organization of the extracellular matrix and modulating the expression of genes involved in exopolysaccharide synthesis and specific sugar transport and two-component systems.

UR - https://www.scopus.com/pages/publications/59649087190

U2 - 10.1128/AEM.01299-08

DO - 10.1128/AEM.01299-08

M3 - Article

C2 - 19028906

AN - SCOPUS:59649087190

SN - 0099-2240

VL - 75

SP - 837

EP - 841

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 3

ER -

Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development

Abstract

Access to Document

Other files and links

Fingerprint

Cite this