TY - JOUR
T1 - Social distancing and extremely preterm births in the initial COVID-19 pandemic period
AU - the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
AU - Shukla, Vivek V.
AU - Carper, Benjamin A.
AU - Ambalavanan, Namasivayam
AU - Rysavy, Matthew A.
AU - Bell, Edward F.
AU - Das, Abhik
AU - Patel, Ravi M.
AU - D’Angio, Carl T.
AU - Watterberg, Kristi L.
AU - Cotten, C. Michael
AU - Merhar, Stephanie L.
AU - Wyckoff, Myra H.
AU - Sánchez, Pablo J.
AU - Kumbhat, Neha
AU - Carlo, Waldemar A.
AU - Polin, Richard A.
AU - Laptook, Abbot R.
AU - Keszler, Martin
AU - Hensman, Angelita M.
AU - Vieira, Elisa
AU - Pierre, Lucille St
AU - Hibbs, Anna Maria
AU - Walsh, Michele C.
AU - Newman, Nancy S.
AU - Smucney, Sarah
AU - Zadell, Arlene
AU - Poindexter, Brenda B.
AU - Schibler, Kurt
AU - Grisby, Cathy
AU - Kirker, Kristin
AU - Wuertz, Sandra
AU - Dudley, Juanita
AU - Beiersdorfer, Traci
AU - Thompson, Julia
AU - Goldberg, Ronald N.
AU - Finkle, Joanne
AU - Fisher, Kimberley A.
AU - Laughon, Matthew M.
AU - Bose, Gennie
AU - Clark, Cindy
AU - Kicklighter, Stephen D.
AU - White, Donna
AU - Carlton, David P.
AU - Loggins, Yvonne
AU - Laursen, Judith
AU - Mackie, Colleen
AU - Bottcher, Diane I.
AU - Bremer, Andrew A.
AU - Higgins, Rosemary D.
AU - Reynolds, Anne Marie
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/7
Y1 - 2024/7
N2 - Hypothesis: Increased social distancing was associated with a lower incidence of extremely preterm live births (EPLB) during the initial COVID-19 pandemic period. Study design: Prospective study at the NICHD Neonatal Research Network sites comparing EPLB (220/7–286/7 weeks) and extremely preterm intrapartum stillbirths (EPIS) rates during the pandemic period (March-July, weeks 9–30 of 2020) with the reference period (same weeks in 2018 and 2019), correlating with state-specific social distancing index (SDI). Results: EPLB and EPIS percentages did not significantly decrease (1.58–1.45%, p = 0.07, and 0.08–0.06%, p = 0.14, respectively). SDI was not significantly correlated with percent change of EPLB (CC = 0.29, 95% CI = −0.12, 0.71) or EPIS (CC = −0.23, 95% CI = −0.65, 0.18). Percent change in mean gestational age was positively correlated with SDI (CC = 0.49, 95% CI = 0.07, 0.91). Conclusions: Increased social distancing was not associated with change in incidence of EPLB but was associated with a higher gestational age of extremely preterm births. ClinicalTrials.gov ID: Generic Database: NCT00063063.
AB - Hypothesis: Increased social distancing was associated with a lower incidence of extremely preterm live births (EPLB) during the initial COVID-19 pandemic period. Study design: Prospective study at the NICHD Neonatal Research Network sites comparing EPLB (220/7–286/7 weeks) and extremely preterm intrapartum stillbirths (EPIS) rates during the pandemic period (March-July, weeks 9–30 of 2020) with the reference period (same weeks in 2018 and 2019), correlating with state-specific social distancing index (SDI). Results: EPLB and EPIS percentages did not significantly decrease (1.58–1.45%, p = 0.07, and 0.08–0.06%, p = 0.14, respectively). SDI was not significantly correlated with percent change of EPLB (CC = 0.29, 95% CI = −0.12, 0.71) or EPIS (CC = −0.23, 95% CI = −0.65, 0.18). Percent change in mean gestational age was positively correlated with SDI (CC = 0.49, 95% CI = 0.07, 0.91). Conclusions: Increased social distancing was not associated with change in incidence of EPLB but was associated with a higher gestational age of extremely preterm births. ClinicalTrials.gov ID: Generic Database: NCT00063063.
UR - https://www.scopus.com/pages/publications/85185665019
U2 - 10.1038/s41372-024-01898-3
DO - 10.1038/s41372-024-01898-3
M3 - Article
C2 - 38388715
AN - SCOPUS:85185665019
SN - 0743-8346
VL - 44
SP - 1050
EP - 1057
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 7
ER -