TY - JOUR
T1 - Single-layer spherical (SLS) vs single-layer (SL) Woven EndoBridge (WEB) device in the treatment of narrow-neck intracranial aneurysms
T2 - a propensity score-matched analysis
AU - WorldWideWEB Investigators
AU - Salim, Hamza Adel
AU - Yedavalli, Vivek
AU - Milhem, Fathi
AU - Adeeb, Nimer
AU - Musmar, Basel
AU - Essibayi, Muhammed Amir
AU - Daraghma, Motaz
AU - Dibas, Mahmoud
AU - Cancelliere, Nicole M.
AU - Diestro, Jose Danilo Bengzon
AU - Algin, Oktay
AU - Ghozy, Sherief
AU - Lay, Sovann V.
AU - Guenego, Adrien
AU - Renieri, Leonardo
AU - Carnevale, Joseph
AU - Saliou, Guillaume
AU - Mastorakos, Panagiotis
AU - Naamani, Kareem El
AU - Shotar, Eimad
AU - Möhlenbruch, Markus
AU - Kral, Michael
AU - Chung, Charlotte
AU - Salem, Mohamed M.
AU - Lylyk, Ivan
AU - Foreman, Paul M.
AU - Shaikh, Hamza
AU - Župančić, Vedran
AU - Hafeez, Muhammad U.
AU - Catapano, Joshua
AU - Waqas, Muhammad
AU - Arslan, Muhammet
AU - Ergun, Onur
AU - Rabinov, James D.
AU - Maingard, Julian
AU - Schirmer, Clemens M.
AU - Piano, Mariangela
AU - Kühn, Anna L.
AU - Michelozzi, Caterina
AU - Starke, Robert M.
AU - Hassan, Ameer
AU - Ogilvie, Mark
AU - Nguyen, Anh
AU - Jones, Jesse
AU - Brinjikji, Waleed
AU - Nawka, Marie T.
AU - Psychogios, Marios
AU - Ulfert, Christian
AU - Siddiqui, Adnan
AU - Levy, Elad I.
N1 - Publisher Copyright:
© The Author(s) 2026.
PY - 2026/12
Y1 - 2026/12
N2 - Data on the use of Woven EndoBridge (WEB) devices in the treatment of narrow-neck intracranial aneurysms (NNA) are limited. We compared the efficacy and safety of single-layer (SL) and single-layer spherical (SLS) WEB devices in treating NNA. We conducted a multicenter retrospective analysis of adult patients with NNA (neck ≤ 4 mm and width-to-neck ratio ≥ 2) treated with SL or SLS WEB devices between January 2011 and December 2022. Patients with fusiform or blister aneurysms, adjunctive treatments, or devices other than SL or SLS were excluded. Propensity score matching was used to adjust for confounding variables. Outcomes included procedural complications, angiographic occlusion rates using the Raymond Roy classification, major device compaction, need for retreatment, and functional outcomes assessed by the modified Rankin Scale (mRS). After matching, resulting in 101 patients in each group, baseline characteristics were well-balanced. Thromboembolic complications occurred in 2.0% of the SLS group and 5.9% of the SL group (P = 0.28). Hemorrhagic complications occurred in 1.0% of the SLS group and 6.4% of the SL group (P = 0.062). Adequate occlusion rates (Raymond Roy grades I and II) were similar between groups (96% in SLS vs. 91% in SL; P = 0.20). Major device compaction was significantly less frequent in the SLS group compared to the SL group (0% vs. 7.6%; P = 0.024). The need for retreatment trended to be lower in the SLS group (1.1% vs. 6.6% in SL; P = 0.12). Functional outcomes (mRS 0–1) at last follow-up were comparable (82% in SLS vs. 86% in SL; P = 0.41). In the treatment of narrow-neck intracranial aneurysms, the SLS WEB device was associated with significantly lower rates of major device compaction compared to the SL device. Reduced compaction may lead to a lower need for retreatment. Overall imaging outcomes and safety profiles were similar between the two devices.
AB - Data on the use of Woven EndoBridge (WEB) devices in the treatment of narrow-neck intracranial aneurysms (NNA) are limited. We compared the efficacy and safety of single-layer (SL) and single-layer spherical (SLS) WEB devices in treating NNA. We conducted a multicenter retrospective analysis of adult patients with NNA (neck ≤ 4 mm and width-to-neck ratio ≥ 2) treated with SL or SLS WEB devices between January 2011 and December 2022. Patients with fusiform or blister aneurysms, adjunctive treatments, or devices other than SL or SLS were excluded. Propensity score matching was used to adjust for confounding variables. Outcomes included procedural complications, angiographic occlusion rates using the Raymond Roy classification, major device compaction, need for retreatment, and functional outcomes assessed by the modified Rankin Scale (mRS). After matching, resulting in 101 patients in each group, baseline characteristics were well-balanced. Thromboembolic complications occurred in 2.0% of the SLS group and 5.9% of the SL group (P = 0.28). Hemorrhagic complications occurred in 1.0% of the SLS group and 6.4% of the SL group (P = 0.062). Adequate occlusion rates (Raymond Roy grades I and II) were similar between groups (96% in SLS vs. 91% in SL; P = 0.20). Major device compaction was significantly less frequent in the SLS group compared to the SL group (0% vs. 7.6%; P = 0.024). The need for retreatment trended to be lower in the SLS group (1.1% vs. 6.6% in SL; P = 0.12). Functional outcomes (mRS 0–1) at last follow-up were comparable (82% in SLS vs. 86% in SL; P = 0.41). In the treatment of narrow-neck intracranial aneurysms, the SLS WEB device was associated with significantly lower rates of major device compaction compared to the SL device. Reduced compaction may lead to a lower need for retreatment. Overall imaging outcomes and safety profiles were similar between the two devices.
KW - Device compaction
KW - Intracranial aneurysm
KW - Narrow-neck aneurysm
KW - Propensity score matching
KW - Single-layer spherical (SLS)
KW - Woven EndoBridge (WEB)
UR - https://www.scopus.com/pages/publications/105031763327
U2 - 10.1007/s10143-025-04077-w
DO - 10.1007/s10143-025-04077-w
M3 - Article
C2 - 41772196
AN - SCOPUS:105031763327
SN - 0344-5607
VL - 49
JO - Neurosurgical Review
JF - Neurosurgical Review
IS - 1
M1 - 256
ER -