Selection of aptamers targeting the sialic acid receptor of hemagglutinin by epitope-specific SELEX

Yeh Hsing Lao; Hui Yu Chiang; Deng Kai Yang; Konan Peck; Lin Chi Chen

doi:10.1039/c4cc03116d

Selection of aptamers targeting the sialic acid receptor of hemagglutinin by epitope-specific SELEX

Yeh Hsing Lao
, Hui Yu Chiang
, Deng Kai Yang
, Konan Peck
, Lin Chi Chen

Pharmaceutical Sciences

National Taiwan University
Academia Sinica - Institute of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

A new SELEX scheme is proposed for the selection of aptamers targeting a specific epitope of a native protein. Anti-sialic acid receptor (SAR) aptamers that inhibit H₁hemagglutination at a low picomole dose are selected accordingly.

Original language	English
Pages (from-to)	8719-8722
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	63
DOIs	https://doi.org/10.1039/c4cc03116d
State	Published - Jul 10 2014

Access to Document

10.1039/c4cc03116d

Cite this

@article{7dc30e25438e4f08bb52d93bac948d68,

title = "Selection of aptamers targeting the sialic acid receptor of hemagglutinin by epitope-specific SELEX",

abstract = "A new SELEX scheme is proposed for the selection of aptamers targeting a specific epitope of a native protein. Anti-sialic acid receptor (SAR) aptamers that inhibit H1hemagglutination at a low picomole dose are selected accordingly.",

author = "Lao, \{Yeh Hsing\} and Chiang, \{Hui Yu\} and Yang, \{Deng Kai\} and Konan Peck and Chen, \{Lin Chi\}",

year = "2014",

month = jul,

day = "10",

doi = "10.1039/c4cc03116d",

language = "English",

volume = "50",

pages = "8719--8722",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "63",

}

TY - JOUR

T1 - Selection of aptamers targeting the sialic acid receptor of hemagglutinin by epitope-specific SELEX

AU - Lao, Yeh Hsing

AU - Chiang, Hui Yu

AU - Yang, Deng Kai

AU - Peck, Konan

AU - Chen, Lin Chi

PY - 2014/7/10

Y1 - 2014/7/10

N2 - A new SELEX scheme is proposed for the selection of aptamers targeting a specific epitope of a native protein. Anti-sialic acid receptor (SAR) aptamers that inhibit H1hemagglutination at a low picomole dose are selected accordingly.

AB - A new SELEX scheme is proposed for the selection of aptamers targeting a specific epitope of a native protein. Anti-sialic acid receptor (SAR) aptamers that inhibit H1hemagglutination at a low picomole dose are selected accordingly.

UR - https://www.scopus.com/pages/publications/84904198902

U2 - 10.1039/c4cc03116d

DO - 10.1039/c4cc03116d

M3 - Article

C2 - 24964092

AN - SCOPUS:84904198902

SN - 1359-7345

VL - 50

SP - 8719

EP - 8722

JO - Chemical Communications

JF - Chemical Communications

IS - 63

ER -

Selection of aptamers targeting the sialic acid receptor of hemagglutinin by epitope-specific SELEX

Abstract

Access to Document

Other files and links

Fingerprint

Cite this