Screening of angiogenesis inhibitors from Korean plants (I)

K. Bae; Y. J. You; J. Y. Park; R. B. An; Y. H. Kim; J. S. Kang; B. Z. Ahn

Screening of angiogenesis inhibitors from Korean plants (I)

K. Bae
, Y. J. You
, J. Y. Park
, R. B. An
, Y. H. Kim
, J. S. Kang
, B. Z. Ahn

Pharmaceutical Sciences

Chungnam National University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Methanol extracts of 94 Korean plants were screened for angiogenesis inhibitors using the tube-like formation assay of HUVEC (Human Umbilical Vein Endothelial Cell) and evaluated for growth inhibitory activity on A549 cells, human lung cancer cells. Extracts of Euphorbia sieboldiana, Adonis amurensis, and Anthriscus sylvestris showed antiangiogenic and growth inhibitory activity at 50 μg/mL. Aristolochia manshuriens and Styrax obassia expressed antiangiogenic activity without growth inhibitory action.

Original language	English
Pages (from-to)	320-324
Number of pages	5
Journal	Korean Journal of Pharmacognosy
Volume	31
Issue number	3
State	Published - 2000

Keywords

Angiogenesis
Aristolochia manshuriens
Cytotoxicity
Styrax obassia

Cite this

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title = "Screening of angiogenesis inhibitors from Korean plants (I)",

abstract = "Methanol extracts of 94 Korean plants were screened for angiogenesis inhibitors using the tube-like formation assay of HUVEC (Human Umbilical Vein Endothelial Cell) and evaluated for growth inhibitory activity on A549 cells, human lung cancer cells. Extracts of Euphorbia sieboldiana, Adonis amurensis, and Anthriscus sylvestris showed antiangiogenic and growth inhibitory activity at 50 μg/mL. Aristolochia manshuriens and Styrax obassia expressed antiangiogenic activity without growth inhibitory action.",

keywords = "Angiogenesis, Aristolochia manshuriens, Cytotoxicity, Styrax obassia",

author = "K. Bae and You, \{Y. J.\} and Park, \{J. Y.\} and An, \{R. B.\} and Kim, \{Y. H.\} and Kang, \{J. S.\} and Ahn, \{B. Z.\}",

year = "2000",

language = "English",

volume = "31",

pages = "320--324",

journal = "Korean Journal of Pharmacognosy",

issn = "0253-3073",

publisher = "Korean Society of Pharmacognosy",

number = "3",

}

TY - JOUR

T1 - Screening of angiogenesis inhibitors from Korean plants (I)

AU - Bae, K.

AU - You, Y. J.

AU - Park, J. Y.

AU - An, R. B.

AU - Kim, Y. H.

AU - Kang, J. S.

AU - Ahn, B. Z.

PY - 2000

Y1 - 2000

N2 - Methanol extracts of 94 Korean plants were screened for angiogenesis inhibitors using the tube-like formation assay of HUVEC (Human Umbilical Vein Endothelial Cell) and evaluated for growth inhibitory activity on A549 cells, human lung cancer cells. Extracts of Euphorbia sieboldiana, Adonis amurensis, and Anthriscus sylvestris showed antiangiogenic and growth inhibitory activity at 50 μg/mL. Aristolochia manshuriens and Styrax obassia expressed antiangiogenic activity without growth inhibitory action.

AB - Methanol extracts of 94 Korean plants were screened for angiogenesis inhibitors using the tube-like formation assay of HUVEC (Human Umbilical Vein Endothelial Cell) and evaluated for growth inhibitory activity on A549 cells, human lung cancer cells. Extracts of Euphorbia sieboldiana, Adonis amurensis, and Anthriscus sylvestris showed antiangiogenic and growth inhibitory activity at 50 μg/mL. Aristolochia manshuriens and Styrax obassia expressed antiangiogenic activity without growth inhibitory action.

KW - Angiogenesis

KW - Aristolochia manshuriens

KW - Cytotoxicity

KW - Styrax obassia

UR - https://www.scopus.com/pages/publications/0034533019

M3 - Article

AN - SCOPUS:0034533019

SN - 0253-3073

VL - 31

SP - 320

EP - 324

JO - Korean Journal of Pharmacognosy

JF - Korean Journal of Pharmacognosy

IS - 3

ER -

Screening of angiogenesis inhibitors from Korean plants (I)

Abstract

Keywords

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