Salicylate ototoxicity: Review and synthesis

Flint A. Boettcher; Richard J. Salvi

doi:10.1016/0196-0709(91)90071-M

Salicylate ototoxicity: Review and synthesis

Flint A. Boettcher
, Richard J. Salvi

Communicative Disorders and Sciences

SUNY Buffalo

Research output: Contribution to journal › Review article › peer-review

77 Scopus citations

Abstract

The effects of salicylates on the auditory system are reviewed. The clinical manifestations of aspirin ototoxicity are described, including changes in the sensitivity and suprathreshold characteristics of hearing, as well as tinnitus. The results of animal experiments on salicylate ototoxicity are discussed, including behavioral, anatomic, and physiologic studies examining the mechanisms of salicylate ototoxicity. The use of salicylates in the study of the basic mechanisms of hearing and hearing loss is also considered.

Original language	English
Pages (from-to)	33-47
Number of pages	15
Journal	American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume	12
Issue number	1
DOIs	https://doi.org/10.1016/0196-0709(91)90071-M
State	Published - 1991

Keywords

aspirin
cochlea
hearing loss
salicylates

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10.1016/0196-0709(91)90071-M

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abstract = "The effects of salicylates on the auditory system are reviewed. The clinical manifestations of aspirin ototoxicity are described, including changes in the sensitivity and suprathreshold characteristics of hearing, as well as tinnitus. The results of animal experiments on salicylate ototoxicity are discussed, including behavioral, anatomic, and physiologic studies examining the mechanisms of salicylate ototoxicity. The use of salicylates in the study of the basic mechanisms of hearing and hearing loss is also considered.",

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AU - Boettcher, Flint A.

AU - Salvi, Richard J.

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AB - The effects of salicylates on the auditory system are reviewed. The clinical manifestations of aspirin ototoxicity are described, including changes in the sensitivity and suprathreshold characteristics of hearing, as well as tinnitus. The results of animal experiments on salicylate ototoxicity are discussed, including behavioral, anatomic, and physiologic studies examining the mechanisms of salicylate ototoxicity. The use of salicylates in the study of the basic mechanisms of hearing and hearing loss is also considered.

KW - aspirin

KW - cochlea

KW - hearing loss

KW - salicylates

UR - https://www.scopus.com/pages/publications/0026021321

U2 - 10.1016/0196-0709(91)90071-M

DO - 10.1016/0196-0709(91)90071-M

M3 - Review article

C2 - 2029065

AN - SCOPUS:0026021321

SN - 0196-0709

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JO - American Journal of Otolaryngology - Head and Neck Medicine and Surgery

JF - American Journal of Otolaryngology - Head and Neck Medicine and Surgery

IS - 1

ER -

Salicylate ototoxicity: Review and synthesis

Abstract

Keywords

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