Role of infections

Kamen Rangelov; Sanjay Sethi

doi:10.1016/j.ccm.2013.09.012

Role of infections

Kamen Rangelov
, Sanjay Sethi

Medicine

SUNY Buffalo

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Abstract

This article represents a review of the current literature on the role of infection in the pathogenesis of chronic obstructive pulmonary disease (COPD), in stable disease, exacerbations, and pneumonia. It outlines the complex interactions between respiratory pathogens and host immune defenses that underlie the clinical manifestations of infection in COPD.

Original language	English
Pages (from-to)	87-100
Number of pages	14
Journal	Clinics in Chest Medicine
Volume	35
Issue number	1
DOIs	https://doi.org/10.1016/j.ccm.2013.09.012
State	Published - Mar 2014

Keywords

Airway colonization
Chronic infection
Infection in COPD
Innate immunity in COPD
New strain exacerbations
Pneumonia and COPD
Vicious-circle hypothesis
Virulence factors

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10.1016/j.ccm.2013.09.012

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title = "Role of infections",

abstract = "This article represents a review of the current literature on the role of infection in the pathogenesis of chronic obstructive pulmonary disease (COPD), in stable disease, exacerbations, and pneumonia. It outlines the complex interactions between respiratory pathogens and host immune defenses that underlie the clinical manifestations of infection in COPD.",

keywords = "Airway colonization, Chronic infection, Infection in COPD, Innate immunity in COPD, New strain exacerbations, Pneumonia and COPD, Vicious-circle hypothesis, Virulence factors",

author = "Kamen Rangelov and Sanjay Sethi",

year = "2014",

month = mar,

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language = "English",

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AU - Sethi, Sanjay

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AB - This article represents a review of the current literature on the role of infection in the pathogenesis of chronic obstructive pulmonary disease (COPD), in stable disease, exacerbations, and pneumonia. It outlines the complex interactions between respiratory pathogens and host immune defenses that underlie the clinical manifestations of infection in COPD.

KW - Airway colonization

KW - Chronic infection

KW - Infection in COPD

KW - Innate immunity in COPD

KW - New strain exacerbations

KW - Pneumonia and COPD

KW - Vicious-circle hypothesis

KW - Virulence factors

UR - https://www.scopus.com/pages/publications/84893501777

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DO - 10.1016/j.ccm.2013.09.012

M3 - Review article

C2 - 24507839

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SN - 0272-5231

VL - 35

SP - 87

EP - 100

JO - Clinics in Chest Medicine

JF - Clinics in Chest Medicine

IS - 1

ER -

Role of infections

Abstract

Keywords

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