Rhodium(II)-catalyzed cross-coupling of diazo compounds

Joørn H. Hansen; Brendan T. Parr; Philip Pelphrey; Quihui Jin; Jochen Autschbach; Huw M.L. Davies

doi:10.1002/anie.201004923

Rhodium(II)-catalyzed cross-coupling of diazo compounds

Joørn H. Hansen
, Brendan T. Parr
, Philip Pelphrey
, Quihui Jin
, Jochen Autschbach
, Huw M.L. Davies

Chemistry

Emory University
SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

114 Scopus citations

Abstract

Nothing left to chance: A convenient protocol for selective cross-coupling of diazo compounds for the convergent synthesis of alkenes was developed (see scheme; EDG=aryl, heteroaryl, vinyl; R=O-alkyl, aryl). The selectivity control elements were identified by ReactIR and DFT calculations and provide a framework for the design of viable diazo coupling reactions.

Original language	English
Pages (from-to)	2544-2548
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	11
DOIs	https://doi.org/10.1002/anie.201004923
State	Published - Mar 7 2011

Keywords

alkenes
carbenoids
cross-coupling reactions
diazo compounds

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10.1002/anie.201004923

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abstract = "Nothing left to chance: A convenient protocol for selective cross-coupling of diazo compounds for the convergent synthesis of alkenes was developed (see scheme; EDG=aryl, heteroaryl, vinyl; R=O-alkyl, aryl). The selectivity control elements were identified by ReactIR and DFT calculations and provide a framework for the design of viable diazo coupling reactions.",

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AU - Autschbach, Jochen

AU - Davies, Huw M.L.

PY - 2011/3/7

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N2 - Nothing left to chance: A convenient protocol for selective cross-coupling of diazo compounds for the convergent synthesis of alkenes was developed (see scheme; EDG=aryl, heteroaryl, vinyl; R=O-alkyl, aryl). The selectivity control elements were identified by ReactIR and DFT calculations and provide a framework for the design of viable diazo coupling reactions.

AB - Nothing left to chance: A convenient protocol for selective cross-coupling of diazo compounds for the convergent synthesis of alkenes was developed (see scheme; EDG=aryl, heteroaryl, vinyl; R=O-alkyl, aryl). The selectivity control elements were identified by ReactIR and DFT calculations and provide a framework for the design of viable diazo coupling reactions.

KW - alkenes

KW - carbenoids

KW - cross-coupling reactions

KW - diazo compounds

UR - https://www.scopus.com/pages/publications/79952259442

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DO - 10.1002/anie.201004923

M3 - Article

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AN - SCOPUS:79952259442

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ER -

Rhodium(II)-catalyzed cross-coupling of diazo compounds

Abstract

Keywords

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