Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodianpopulations with dysglycemia in the U.S. and in Cambodia

Richard Feinn; Angela Bermudez-Millan; S. Megan Berthold; Thomas Buckley; Judah Emmanuel; Loraine Fraser-King; Ien Srey Horn; Lim Keuky; Sengly Kong; Theanvy Kuoch; Sara O'Donnell; Jennifer P. Read; Mary Scully; Julie Wagner

doi:10.1016/j.dsx.2021.102374

Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodianpopulations with dysglycemia in the U.S. and in Cambodia

Richard Feinn
, Angela Bermudez-Millan
, S. Megan Berthold
, Thomas Buckley
, Judah Emmanuel
, Loraine Fraser-King
, Ien Srey Horn
, Lim Keuky
, Sengly Kong
, Theanvy Kuoch
, Sara O'Donnell
, Jennifer P. Read
, Mary Scully
, Julie Wagner

Psychology

Quinnipiac University
University of Connecticut
UConn School of Social Work
Cambodian Diabetes Association
Khmer Health Advocates
SUNY Buffalo
UConn Schools of Medicine and Dental Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Background and aims: Facial flushing after drinking alcohol, common among Asians, is a phenotype for genes involved in alcohol metabolism. Methods: We investigated cross-sectional associations between flushing, alcohol use, blood pressure (BP) and HbA1c among (n = 287) Cambodians with dysglycemia in Cambodia and in the U.S. Participants were categorized as Abstainers, Flushers who drink, or Non-flushers who drink. Results: Flushers and Non-flushers had similar alcohol use. Flushers had higher BP than Non-flushers and Abstainers, even after controlling for confounders. Findings were similar across countries. Drinkers had higher HbA1c than Abstainers. Conclusions: Future research should examine whether reducing alcohol improves cardiometabolic outcomes.

Original language	English
Article number	102374
Journal	Diabetes and Metabolic Syndrome: Clinical Research and Reviews
Volume	16
Issue number	1
DOIs	https://doi.org/10.1016/j.dsx.2021.102374
State	Published - Jan 2022

Keywords

Alcohol
Blood pressure
Cambodia
Facial flushing
HbA1c
Type 2 diabetes

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10.1016/j.dsx.2021.102374

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Feinn, R., Bermudez-Millan, A., Berthold, S. M., Buckley, T., Emmanuel, J., Fraser-King, L., Horn, I. S., Keuky, L., Kong, S., Kuoch, T., O'Donnell, S., Read, J. P., Scully, M., & Wagner, J. (2022). Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodianpopulations with dysglycemia in the U.S. and in Cambodia. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 16(1), Article 102374. https://doi.org/10.1016/j.dsx.2021.102374

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title = "Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodianpopulations with dysglycemia in the U.S. and in Cambodia",

abstract = "Background and aims: Facial flushing after drinking alcohol, common among Asians, is a phenotype for genes involved in alcohol metabolism. Methods: We investigated cross-sectional associations between flushing, alcohol use, blood pressure (BP) and HbA1c among (n = 287) Cambodians with dysglycemia in Cambodia and in the U.S. Participants were categorized as Abstainers, Flushers who drink, or Non-flushers who drink. Results: Flushers and Non-flushers had similar alcohol use. Flushers had higher BP than Non-flushers and Abstainers, even after controlling for confounders. Findings were similar across countries. Drinkers had higher HbA1c than Abstainers. Conclusions: Future research should examine whether reducing alcohol improves cardiometabolic outcomes.",

keywords = "Alcohol, Blood pressure, Cambodia, Facial flushing, HbA1c, Type 2 diabetes",

author = "Richard Feinn and Angela Bermudez-Millan and Berthold, \{S. Megan\} and Thomas Buckley and Judah Emmanuel and Loraine Fraser-King and Horn, \{Ien Srey\} and Lim Keuky and Sengly Kong and Theanvy Kuoch and Sara O'Donnell and Read, \{Jennifer P.\} and Mary Scully and Julie Wagner",

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year = "2022",

month = jan,

doi = "10.1016/j.dsx.2021.102374",

language = "English",

volume = "16",

journal = "Diabetes and Metabolic Syndrome: Clinical Research and Reviews",

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Feinn, R, Bermudez-Millan, A, Berthold, SM, Buckley, T, Emmanuel, J, Fraser-King, L, Horn, IS, Keuky, L, Kong, S, Kuoch, T, O'Donnell, S, Read, JP, Scully, M & Wagner, J 2022, 'Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodianpopulations with dysglycemia in the U.S. and in Cambodia', Diabetes and Metabolic Syndrome: Clinical Research and Reviews, vol. 16, no. 1, 102374. https://doi.org/10.1016/j.dsx.2021.102374

Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodianpopulations with dysglycemia in the U.S. and in Cambodia. / Feinn, Richard; Bermudez-Millan, Angela; Berthold, S. Megan et al.
In: Diabetes and Metabolic Syndrome: Clinical Research and Reviews, Vol. 16, No. 1, 102374, 01.2022.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodianpopulations with dysglycemia in the U.S. and in Cambodia

AU - Feinn, Richard

AU - Bermudez-Millan, Angela

AU - Berthold, S. Megan

AU - Buckley, Thomas

AU - Emmanuel, Judah

AU - Fraser-King, Loraine

AU - Horn, Ien Srey

AU - Keuky, Lim

AU - Kong, Sengly

AU - Kuoch, Theanvy

AU - O'Donnell, Sara

AU - Read, Jennifer P.

AU - Scully, Mary

AU - Wagner, Julie

PY - 2022/1

Y1 - 2022/1

N2 - Background and aims: Facial flushing after drinking alcohol, common among Asians, is a phenotype for genes involved in alcohol metabolism. Methods: We investigated cross-sectional associations between flushing, alcohol use, blood pressure (BP) and HbA1c among (n = 287) Cambodians with dysglycemia in Cambodia and in the U.S. Participants were categorized as Abstainers, Flushers who drink, or Non-flushers who drink. Results: Flushers and Non-flushers had similar alcohol use. Flushers had higher BP than Non-flushers and Abstainers, even after controlling for confounders. Findings were similar across countries. Drinkers had higher HbA1c than Abstainers. Conclusions: Future research should examine whether reducing alcohol improves cardiometabolic outcomes.

AB - Background and aims: Facial flushing after drinking alcohol, common among Asians, is a phenotype for genes involved in alcohol metabolism. Methods: We investigated cross-sectional associations between flushing, alcohol use, blood pressure (BP) and HbA1c among (n = 287) Cambodians with dysglycemia in Cambodia and in the U.S. Participants were categorized as Abstainers, Flushers who drink, or Non-flushers who drink. Results: Flushers and Non-flushers had similar alcohol use. Flushers had higher BP than Non-flushers and Abstainers, even after controlling for confounders. Findings were similar across countries. Drinkers had higher HbA1c than Abstainers. Conclusions: Future research should examine whether reducing alcohol improves cardiometabolic outcomes.

KW - Alcohol

KW - Blood pressure

KW - Cambodia

KW - Facial flushing

KW - HbA1c

KW - Type 2 diabetes

UR - https://www.scopus.com/pages/publications/85121917679

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DO - 10.1016/j.dsx.2021.102374

M3 - Article

C2 - 34973623

AN - SCOPUS:85121917679

SN - 1871-4021

VL - 16

JO - Diabetes and Metabolic Syndrome: Clinical Research and Reviews

JF - Diabetes and Metabolic Syndrome: Clinical Research and Reviews

IS - 1

M1 - 102374

ER -

Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodianpopulations with dysglycemia in the U.S. and in Cambodia

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Keywords

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