Regioselective syntheses and some in vivo properties of "benzochlorin" analogues prepared from methyl 9-deoxymesopyropheophorbide

Ravindra K. Pandey; Sashikumar N. Mettath; Sapna Gupta; William R. Potter; Thomas J. Dougherty; Kevin M. Smith

doi:10.1016/0960-894X(95)00129-H

Regioselective syntheses and some in vivo properties of "benzochlorin" analogues prepared from methyl 9-deoxymesopyropheophorbide

Ravindra K. Pandey
, Sashikumar N. Mettath
, Sapna Gupta
, William R. Potter
, Thomas J. Dougherty
, Kevin M. Smith

Institute for Lasers Photonics and Biophotonics

Division of Radiation Medicine
University of California at Davis

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Starting from methyl 9-deoxymesopyropheophorbide-a 5, regioselective synthesis of a series of benzochlorins was achieved. These compounds have long wavelength absorptions in the range of 710-756 nm. The in vivo spectroscopic properties as well as the uptake and clearance characteristics of some of these compounds (e.g. 13) were determined by use of in vivo reflection spectroscopy.

Original language	English
Pages (from-to)	857-860
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	5
Issue number	8
DOIs	https://doi.org/10.1016/0960-894X(95)00129-H
State	Published - Apr 20 1995

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abstract = "Starting from methyl 9-deoxymesopyropheophorbide-a 5, regioselective synthesis of a series of benzochlorins was achieved. These compounds have long wavelength absorptions in the range of 710-756 nm. The in vivo spectroscopic properties as well as the uptake and clearance characteristics of some of these compounds (e.g. 13) were determined by use of in vivo reflection spectroscopy.",

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T1 - Regioselective syntheses and some in vivo properties of "benzochlorin" analogues prepared from methyl 9-deoxymesopyropheophorbide

AU - Pandey, Ravindra K.

AU - Mettath, Sashikumar N.

AU - Gupta, Sapna

AU - Potter, William R.

AU - Dougherty, Thomas J.

AU - Smith, Kevin M.

PY - 1995/4/20

Y1 - 1995/4/20

N2 - Starting from methyl 9-deoxymesopyropheophorbide-a 5, regioselective synthesis of a series of benzochlorins was achieved. These compounds have long wavelength absorptions in the range of 710-756 nm. The in vivo spectroscopic properties as well as the uptake and clearance characteristics of some of these compounds (e.g. 13) were determined by use of in vivo reflection spectroscopy.

AB - Starting from methyl 9-deoxymesopyropheophorbide-a 5, regioselective synthesis of a series of benzochlorins was achieved. These compounds have long wavelength absorptions in the range of 710-756 nm. The in vivo spectroscopic properties as well as the uptake and clearance characteristics of some of these compounds (e.g. 13) were determined by use of in vivo reflection spectroscopy.

UR - https://www.scopus.com/pages/publications/0028925474

U2 - 10.1016/0960-894X(95)00129-H

DO - 10.1016/0960-894X(95)00129-H

M3 - Article

AN - SCOPUS:0028925474

SN - 0960-894X

VL - 5

SP - 857

EP - 860

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 8

ER -

Regioselective syntheses and some in vivo properties of "benzochlorin" analogues prepared from methyl 9-deoxymesopyropheophorbide

Abstract

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