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Recent advances in computational modeling of the effects of micro/nanoparticle interactions on vesicle morphology

  • SUNY Buffalo

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Computational modeling has become essential in advancing our understanding of complex biological processes. Fluid lipid vesicles serve as ideal models for studying the interactions between cells, cell membranes, and micro/nanoparticles. Various computational approaches have been developed in the past 20 years and are increasingly utilized to investigate these interactions across different time and length scales. This book chapter reviews the modeling techniques employed to simulate vesicle–particle interactions and complex dynamics, including both continuum and particle-based methods. Furthermore, we discuss recent findings at the forefront of this field generated by computational modeling, which provides insight into the physical phenomena governing vesicle deformation, particle wrapping, and membrane remodeling.

Original languageEnglish
Title of host publicationAdvances in Biomembranes and Lipid Self-Assembly
EditorsAleš Iglič, Michael Rappolt, Patricia Losada-Pérez
PublisherElsevier B.V.
Pages61-85
Number of pages25
ISBN (Print)9780443428234
DOIs
StatePublished - Jan 2025

Publication series

NameAdvances in Biomembranes and Lipid Self-Assembly
Volume42
ISSN (Print)2451-9634

Keywords

  • Active particle
  • Dissipative particle dynamics
  • Membrane
  • Micro/nanoparticle
  • Molecular dynamics
  • Shape anisotropy
  • Triangulated surface model
  • Vesicle

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