TY - JOUR
T1 - Rates and associated risk factors for cataract surgery complications in academic medical centers
AU - Sight Outcomes Research Collaborative (SOURCE) Consortium
AU - Danziger, Gabriella S.
AU - Li, Yang
AU - Andrews, Chris A.
AU - Marwah, Shikha
AU - Rivera, Adovich S.
AU - Zhou, Xueqing
AU - Chaudhury, Azraa S.
AU - Mohamedali, Alaa
AU - Aneja, Anushree
AU - Kanwar, Kunal
AU - Shah, Richa
AU - Ahuja, Arun
AU - Evans, Charlesnika T.
AU - Kho, Abel N.
AU - Stein, Joshua D.
AU - Amin, Sejal
AU - Edwards, Paul A.
AU - Srikumaran, Divya
AU - Woreta, Fasika
AU - Schultz, Jeffrey S.
AU - Shrivastava, Anurag
AU - Ahmad, Baseer
AU - Pasquale, Louis
AU - Lee, Rachel
AU - Bryar, Paul J.
AU - French, Dustin D.
AU - Hribar, Michelle
AU - Thomas, Merina
AU - Vanderbeek, Brian L.
AU - Pershing, Suzann
AU - Wang, Sophia Y.
AU - Deiner, Michael
AU - Sun, Catherine
AU - Patnaik, Jennifer
AU - Subramanian, Prem
AU - Munir, Saleha
AU - Munir, Wuqaas
AU - Ganapathy, Preethi
AU - Stein, Joshua
AU - De Lott, Lindsey
AU - Ramachandran, Rajeev
AU - Feldman, Robert
AU - Stagg, Brian C.
AU - Wirostko, Barbara
AU - McMillian, Brian
AU - Sheybani, Arsham
AU - Sarrapour, Soshian
AU - Harris-Nwanyanwu, Kristen
N1 - Publisher Copyright:
Copyright © 2025 Published by Wolters Kluwer on behalf of ASCRS and ESCRS
PY - 2026/3
Y1 - 2026/3
N2 - Purpose: – To evaluate sociodemographic and clinical factors with postoperative complications after cataract surgery at academic medical centers in the United States.Setting: – 16 U.S. academic medical centers contributing to the Sight Outcomes Research Collaborative (SOURCE) big data repository.Design: – Retrospective, multicenter cohort study.Methods: – Adults undergoing cataract surgery between 2010 and 2023 were identified from the SOURCE database. Sociodemographic and clinical predictors including race, ethnicity, primary language, and prior intraocular surgery were assessed. Postoperative complications within 6 months were identified using Current Procedural Terminology/International Classification of Diseases codes. Multivariate cox regression estimated hazard ratios with 95% confidence intervals.Results: – 78 565 eyes were analyzed (mean age 70.8 ± 8.9 years, 59% female, 12.6% Black). At 6 months, 1.49% of eyes developed a complication and 0.10 developed a severe adverse complication. Independent predictors of any complication included male sex (hazard ratio [HR] 1.14; P < .01), Black race (HR 1.66; P < .01), complex surgery (HR 1.23; P < .01), combined intraocular procedures (HR 1.33; P < .01), prior intraocular surgery (HR 1.18; P < .01), and poorer preoperative vision (HR 1.10; P < .01). Severe adverse complications were more likely among men (HR 1.54; P = .02) and those with poorer vision (HR 1.62; P < .01), but less likely with increasing age (HR 0.95; P < .01), urban residence (HR 0.33; P < .01), and having 1 or more children in the household (HR 0.32; P = .03).Conclusions: – Sociodemographic and clinical factors that increased risk of postoperative outcomes after cataract surgery included Black race, male sex, and poor preoperative vision. Older age, urban residence, and children in the household were protective. Incorporating social determinants of health into perioperative risk stratification may improve surgical equity and outcomes.
AB - Purpose: – To evaluate sociodemographic and clinical factors with postoperative complications after cataract surgery at academic medical centers in the United States.Setting: – 16 U.S. academic medical centers contributing to the Sight Outcomes Research Collaborative (SOURCE) big data repository.Design: – Retrospective, multicenter cohort study.Methods: – Adults undergoing cataract surgery between 2010 and 2023 were identified from the SOURCE database. Sociodemographic and clinical predictors including race, ethnicity, primary language, and prior intraocular surgery were assessed. Postoperative complications within 6 months were identified using Current Procedural Terminology/International Classification of Diseases codes. Multivariate cox regression estimated hazard ratios with 95% confidence intervals.Results: – 78 565 eyes were analyzed (mean age 70.8 ± 8.9 years, 59% female, 12.6% Black). At 6 months, 1.49% of eyes developed a complication and 0.10 developed a severe adverse complication. Independent predictors of any complication included male sex (hazard ratio [HR] 1.14; P < .01), Black race (HR 1.66; P < .01), complex surgery (HR 1.23; P < .01), combined intraocular procedures (HR 1.33; P < .01), prior intraocular surgery (HR 1.18; P < .01), and poorer preoperative vision (HR 1.10; P < .01). Severe adverse complications were more likely among men (HR 1.54; P = .02) and those with poorer vision (HR 1.62; P < .01), but less likely with increasing age (HR 0.95; P < .01), urban residence (HR 0.33; P < .01), and having 1 or more children in the household (HR 0.32; P = .03).Conclusions: – Sociodemographic and clinical factors that increased risk of postoperative outcomes after cataract surgery included Black race, male sex, and poor preoperative vision. Older age, urban residence, and children in the household were protective. Incorporating social determinants of health into perioperative risk stratification may improve surgical equity and outcomes.
UR - https://www.scopus.com/pages/publications/105030866725
U2 - 10.1097/j.jcrs.0000000000001822
DO - 10.1097/j.jcrs.0000000000001822
M3 - Article
C2 - 41168667
AN - SCOPUS:105030866725
SN - 0886-3350
VL - 52
SP - 223
EP - 230
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
IS - 3
ER -