Profiles and Predictors of Treatment-Resistant Opioid Use Disorder (TROUD): A Secondary Data Analysis of Treatment Episode Data Set’s 2017 Admissions

David A. Patterson Silver Wolf; Catherine Dulmus; Greg Wilding; Amy Barczykowski; Jihnhee Yu; Sara Beeler-Stinn; Autumn Asher Blackdeer; Steven Harvey; Nicole M. Rodriguez

doi:10.1080/07347324.2021.1895015

Profiles and Predictors of Treatment-Resistant Opioid Use Disorder (TROUD): A Secondary Data Analysis of Treatment Episode Data Set’s 2017 Admissions

David A. Patterson Silver Wolf
, Catherine Dulmus
, Greg Wilding
, Amy Barczykowski
, Jihnhee Yu
, Sara Beeler-Stinn
, Autumn Asher Blackdeer
, Steven Harvey
, Nicole M. Rodriguez

Washington University St. Louis
SUNY Buffalo
Inc.

Research output: Contribution to journal › Article › peer-review

Abstract

Though behavioral interventions and medications have shown efficacy for individuals suffering from an opioid use disorder (OUD), there is a substantial sub-population that does not respond to currently available treatments. Through a secondary data analysis, this study finds evidence for the existence of treatment-resistant opioid use disorder (TROUD) by determining and examining factors associated with low and high treatment groups. This study provides evidence that failure to successfully complete treatment is related to the disorder’s resistance, thereby opening new clinical and research paths that can help in designing personalized therapies to treat TROUD.

Original language	English
Pages (from-to)	517-532
Number of pages	16
Journal	Alcoholism Treatment Quarterly
Volume	39
Issue number	4
DOIs	https://doi.org/10.1080/07347324.2021.1895015
State	Published - 2021

Keywords

Substance use disorder
opioid use disorder
predictive models
risk factors
treatment resistance

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10.1080/07347324.2021.1895015

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Patterson Silver Wolf, D. A., Dulmus, C., Wilding, G., Barczykowski, A., Yu, J., Beeler-Stinn, S., Asher Blackdeer, A., Harvey, S., & Rodriguez, N. M. (2021). Profiles and Predictors of Treatment-Resistant Opioid Use Disorder (TROUD): A Secondary Data Analysis of Treatment Episode Data Set’s 2017 Admissions. Alcoholism Treatment Quarterly, 39(4), 517-532. https://doi.org/10.1080/07347324.2021.1895015

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title = "Profiles and Predictors of Treatment-Resistant Opioid Use Disorder (TROUD): A Secondary Data Analysis of Treatment Episode Data Set{\textquoteright}s 2017 Admissions",

abstract = "Though behavioral interventions and medications have shown efficacy for individuals suffering from an opioid use disorder (OUD), there is a substantial sub-population that does not respond to currently available treatments. Through a secondary data analysis, this study finds evidence for the existence of treatment-resistant opioid use disorder (TROUD) by determining and examining factors associated with low and high treatment groups. This study provides evidence that failure to successfully complete treatment is related to the disorder{\textquoteright}s resistance, thereby opening new clinical and research paths that can help in designing personalized therapies to treat TROUD.",

keywords = "Substance use disorder, opioid use disorder, predictive models, risk factors, treatment resistance",

author = "\{Patterson Silver Wolf\}, \{David A.\} and Catherine Dulmus and Greg Wilding and Amy Barczykowski and Jihnhee Yu and Sara Beeler-Stinn and \{Asher Blackdeer\}, Autumn and Steven Harvey and Rodriguez, \{Nicole M.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Taylor \& Francis.",

year = "2021",

doi = "10.1080/07347324.2021.1895015",

language = "English",

volume = "39",

pages = "517--532",

journal = "Alcoholism Treatment Quarterly",

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Patterson Silver Wolf, DA, Dulmus, C , Wilding, G, Barczykowski, A, Yu, J, Beeler-Stinn, S, Asher Blackdeer, A, Harvey, S & Rodriguez, NM 2021, 'Profiles and Predictors of Treatment-Resistant Opioid Use Disorder (TROUD): A Secondary Data Analysis of Treatment Episode Data Set’s 2017 Admissions', Alcoholism Treatment Quarterly, vol. 39, no. 4, pp. 517-532. https://doi.org/10.1080/07347324.2021.1895015

TY - JOUR

T1 - Profiles and Predictors of Treatment-Resistant Opioid Use Disorder (TROUD)

T2 - A Secondary Data Analysis of Treatment Episode Data Set’s 2017 Admissions

AU - Patterson Silver Wolf, David A.

AU - Dulmus, Catherine

AU - Wilding, Greg

AU - Barczykowski, Amy

AU - Yu, Jihnhee

AU - Beeler-Stinn, Sara

AU - Asher Blackdeer, Autumn

AU - Harvey, Steven

AU - Rodriguez, Nicole M.

PY - 2021

Y1 - 2021

N2 - Though behavioral interventions and medications have shown efficacy for individuals suffering from an opioid use disorder (OUD), there is a substantial sub-population that does not respond to currently available treatments. Through a secondary data analysis, this study finds evidence for the existence of treatment-resistant opioid use disorder (TROUD) by determining and examining factors associated with low and high treatment groups. This study provides evidence that failure to successfully complete treatment is related to the disorder’s resistance, thereby opening new clinical and research paths that can help in designing personalized therapies to treat TROUD.

AB - Though behavioral interventions and medications have shown efficacy for individuals suffering from an opioid use disorder (OUD), there is a substantial sub-population that does not respond to currently available treatments. Through a secondary data analysis, this study finds evidence for the existence of treatment-resistant opioid use disorder (TROUD) by determining and examining factors associated with low and high treatment groups. This study provides evidence that failure to successfully complete treatment is related to the disorder’s resistance, thereby opening new clinical and research paths that can help in designing personalized therapies to treat TROUD.

KW - Substance use disorder

KW - opioid use disorder

KW - predictive models

KW - risk factors

KW - treatment resistance

UR - https://www.scopus.com/pages/publications/85102503714

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DO - 10.1080/07347324.2021.1895015

M3 - Article

AN - SCOPUS:85102503714

SN - 0734-7324

VL - 39

SP - 517

EP - 532

JO - Alcoholism Treatment Quarterly

JF - Alcoholism Treatment Quarterly

IS - 4

ER -

Profiles and Predictors of Treatment-Resistant Opioid Use Disorder (TROUD): A Secondary Data Analysis of Treatment Episode Data Set’s 2017 Admissions

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Keywords

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