Primary structure of two nonallelic β-globin chains from DBA/2 mice

M. D. Garrick; R. A. Popp; B. P. Alter

doi:10.1007/BF00554548

Primary structure of two nonallelic β-globin chains from DBA/2 mice

M. D. Garrick
, R. A. Popp
, B. P. Alter

Biochemistry

Oak Ridge National Laboratory
Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The amino acid sequences of the β major and β minor globin chains from DBA/2 mice have been determined. This information is of interest because DBA/2 mice are the strain of origin for most murine erythroleukemia lines. The primary structure of DBA/2 β globins agrees completely with that predicted from the coding properties of BALB/c β globin genes. This identity does not support a rapid evolutionary divergence in inbred mouse strains, at least at these loci in these strains.

Original language	English
Pages (from-to)	391-399
Number of pages	9
Journal	Biochemical Genetics
Volume	25
Issue number	5-6
DOIs	https://doi.org/10.1007/BF00554548
State	Published - Jun 1987

Keywords

β major and β minor globin
amino acid sequence
inbred mice
murine erythroleukemia
protein evolution

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abstract = "The amino acid sequences of the β major and β minor globin chains from DBA/2 mice have been determined. This information is of interest because DBA/2 mice are the strain of origin for most murine erythroleukemia lines. The primary structure of DBA/2 β globins agrees completely with that predicted from the coding properties of BALB/c β globin genes. This identity does not support a rapid evolutionary divergence in inbred mouse strains, at least at these loci in these strains.",

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year = "1987",

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AU - Garrick, M. D.

AU - Popp, R. A.

AU - Alter, B. P.

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N2 - The amino acid sequences of the β major and β minor globin chains from DBA/2 mice have been determined. This information is of interest because DBA/2 mice are the strain of origin for most murine erythroleukemia lines. The primary structure of DBA/2 β globins agrees completely with that predicted from the coding properties of BALB/c β globin genes. This identity does not support a rapid evolutionary divergence in inbred mouse strains, at least at these loci in these strains.

AB - The amino acid sequences of the β major and β minor globin chains from DBA/2 mice have been determined. This information is of interest because DBA/2 mice are the strain of origin for most murine erythroleukemia lines. The primary structure of DBA/2 β globins agrees completely with that predicted from the coding properties of BALB/c β globin genes. This identity does not support a rapid evolutionary divergence in inbred mouse strains, at least at these loci in these strains.

KW - β major and β minor globin

KW - amino acid sequence

KW - inbred mice

KW - murine erythroleukemia

KW - protein evolution

UR - https://www.scopus.com/pages/publications/0023225363

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DO - 10.1007/BF00554548

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AN - SCOPUS:0023225363

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EP - 399

JO - Biochemical Genetics

JF - Biochemical Genetics

IS - 5-6

ER -

Primary structure of two nonallelic β-globin chains from DBA/2 mice

Abstract

Keywords

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