Abstract
Preparation of biomacromolecules for structural biology studies is a complex and time-consuming process. The goal is to produce a highly concentrated, highly pure product that is often shipped to large facilities with tools to prepare the samples for crystallization trials or for measurements at synchrotrons and cryoEM centers. The aim of this article is to provide guidance and to discuss general considerations for shipping biomacromolecular samples. Details are also provided about shipping samples for specific experiment types, including solution- and cryogenic-based techniques. These guidelines are provided with the hope that the time and energy invested in sample preparation is not lost due to shipping logistics.
| Original language | English |
|---|---|
| Pages (from-to) | 165-172 |
| Number of pages | 8 |
| Journal | Acta Crystallographica Section F: Structural Biology Communications |
| Volume | 80 |
| Issue number | Pt 8 |
| DOIs | |
| State | Published - Aug 1 2024 |
Keywords
- SAXS/WAXS
- X-ray crystallography
- cryoEM
- sample preparation
- shipping biomacromolecules
- structural biology
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