Abstract
In recent years, a number or review articles describing the utility of porphyrin-based compounds in photodynamic therapy have been published. Currently, efforts are also underway in various laboratories to increase the tumor-specificity by developing target-specific photosensitizers. One of such attempts has been to synthesize a series of carbohydrate-porphyrin conjugates and investigate their ability to target carbohydrate- recognized proteins, which are known for their high expression in certain tumors. The present article is focused on the synthesis and biological significance of carbohydrate conjugated photosensitizers.
| Original language | English |
|---|---|
| Pages (from-to) | 241-268 |
| Number of pages | 28 |
| Journal | Anti-Cancer Agents in Medicinal Chemistry |
| Volume | 8 |
| Issue number | 3 |
| DOIs | |
| State | Published - Apr 2008 |
Keywords
- Carbohydrate-Porphyrin conjugates
- Photodynamic therapy
- Photofrin®
- Porphyrin
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