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Polypeptide backbone, Cβ and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectin

  • Surya V.S.R.K. Pulavarti
  • , Alexander Eletsky
  • , Yuanpeng J. Huang
  • , Thomas B. Acton
  • , Rong Xiao
  • , John K. Everett
  • , Gaetano T. Montelione
  • , Thomas Szyperski
  • SUNY Buffalo
  • Northeast Structural Genomics Consortium
  • Rutgers - The State University of New Jersey, New Brunswick
  • Northeast Structural Genomics Consortium

Research output: Contribution to journalArticlepeer-review

Abstract

The 500 kDa protein plectin is essential for the cytoskeletal organization of most mammalian cells and it is up-regulated in some types of cancer. Here, we report nearly complete sequence-specific polypeptide backbone, 13Cβ and methyl group resonance assignments for 24 kDa human plectin(4403–4606) containing the C-terminal plectin repeat domain 6.

Original languageEnglish
Pages (from-to)135-138
Number of pages4
JournalBiomolecular NMR Assignments
Volume9
Issue number1
DOIs
StatePublished - Apr 2015

Keywords

  • Cytoskeletal linker protein
  • HCPIN
  • Plakin repeat domain
  • Plectin repeat domain
  • Selective isotope labeling
  • Structural genomics

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