Polylactide inhibition of carcinoma cell growth in vitro

John H. Campbell; Laura Edsberg; Anne E. Meyer

doi:10.1016/0278-2391(94)90014-0

Polylactide inhibition of carcinoma cell growth in vitro

John H. Campbell
, Laura Edsberg
, Anne E. Meyer

Department of Oral and Maxillofacial Surgery

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Normal fibroblasts and epithelial tumor cells were challenged by exposure for 24 hours to extracts of a pure metal, a metal alloy, and a polymer used in facial reconstruction to assess cellular growth effects. While none of these materials significantly altered fibroblast growth rates, poly-L-lactide inhibited carcinoma cell growth at 5.0% extract concentration. No carcinoma cell growth effects were seen from exposure to stainless steel or commercially pure titanium extracts.

Original language	English
Pages (from-to)	49-51
Number of pages	3
Journal	Journal of Oral and Maxillofacial Surgery
Volume	52
Issue number	1
DOIs	https://doi.org/10.1016/0278-2391(94)90014-0
State	Published - Jan 1994

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@article{672890a7aaa6411cb41cd485362c9ebf,

title = "Polylactide inhibition of carcinoma cell growth in vitro",

abstract = "Normal fibroblasts and epithelial tumor cells were challenged by exposure for 24 hours to extracts of a pure metal, a metal alloy, and a polymer used in facial reconstruction to assess cellular growth effects. While none of these materials significantly altered fibroblast growth rates, poly-L-lactide inhibited carcinoma cell growth at 5.0\% extract concentration. No carcinoma cell growth effects were seen from exposure to stainless steel or commercially pure titanium extracts.",

author = "Campbell, \{John H.\} and Laura Edsberg and Meyer, \{Anne E.\}",

year = "1994",

month = jan,

doi = "10.1016/0278-2391(94)90014-0",

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journal = "Journal of Oral and Maxillofacial Surgery",

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T1 - Polylactide inhibition of carcinoma cell growth in vitro

AU - Campbell, John H.

AU - Edsberg, Laura

AU - Meyer, Anne E.

PY - 1994/1

Y1 - 1994/1

N2 - Normal fibroblasts and epithelial tumor cells were challenged by exposure for 24 hours to extracts of a pure metal, a metal alloy, and a polymer used in facial reconstruction to assess cellular growth effects. While none of these materials significantly altered fibroblast growth rates, poly-L-lactide inhibited carcinoma cell growth at 5.0% extract concentration. No carcinoma cell growth effects were seen from exposure to stainless steel or commercially pure titanium extracts.

AB - Normal fibroblasts and epithelial tumor cells were challenged by exposure for 24 hours to extracts of a pure metal, a metal alloy, and a polymer used in facial reconstruction to assess cellular growth effects. While none of these materials significantly altered fibroblast growth rates, poly-L-lactide inhibited carcinoma cell growth at 5.0% extract concentration. No carcinoma cell growth effects were seen from exposure to stainless steel or commercially pure titanium extracts.

UR - https://www.scopus.com/pages/publications/0028010746

U2 - 10.1016/0278-2391(94)90014-0

DO - 10.1016/0278-2391(94)90014-0

M3 - Article

C2 - 8263643

AN - SCOPUS:0028010746

SN - 0278-2391

VL - 52

SP - 49

EP - 51

JO - Journal of Oral and Maxillofacial Surgery

JF - Journal of Oral and Maxillofacial Surgery

IS - 1

ER -

Polylactide inhibition of carcinoma cell growth in vitro

Abstract

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