Platelet Monoamine Oxidase in Early Childhood Autism

Donald J. Cohen; J. Gerald Young; Jerome A. Roth

doi:10.1001/archpsyc.1977.01770170044003

Platelet Monoamine Oxidase in Early Childhood Autism

Donald J. Cohen
, J. Gerald Young
, Jerome A. Roth

Pharmacology and Toxicology

Yale University

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Platelet monoamine oxidase (MAO) activity was studied in 31 individuals suffering from early childhood autism and was not significantly different from that found in normal children or adults. In the autistic children, MAO activity decreased with age, and there was a trend toward greater platelet MAO activity in prepubertal and pubertal male autistic children relative to normal male children. Total platelet counts were not elevated in autistic children.

Original language	English
Pages (from-to)	534-537
Number of pages	4
Journal	Archives of General Psychiatry
Volume	34
Issue number	5
DOIs	https://doi.org/10.1001/archpsyc.1977.01770170044003
State	Published - May 1977

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title = "Platelet Monoamine Oxidase in Early Childhood Autism",

abstract = "Platelet monoamine oxidase (MAO) activity was studied in 31 individuals suffering from early childhood autism and was not significantly different from that found in normal children or adults. In the autistic children, MAO activity decreased with age, and there was a trend toward greater platelet MAO activity in prepubertal and pubertal male autistic children relative to normal male children. Total platelet counts were not elevated in autistic children.",

author = "Cohen, \{Donald J.\} and Young, \{J. Gerald\} and Roth, \{Jerome A.\}",

year = "1977",

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language = "English",

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T1 - Platelet Monoamine Oxidase in Early Childhood Autism

AU - Cohen, Donald J.

AU - Young, J. Gerald

AU - Roth, Jerome A.

PY - 1977/5

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N2 - Platelet monoamine oxidase (MAO) activity was studied in 31 individuals suffering from early childhood autism and was not significantly different from that found in normal children or adults. In the autistic children, MAO activity decreased with age, and there was a trend toward greater platelet MAO activity in prepubertal and pubertal male autistic children relative to normal male children. Total platelet counts were not elevated in autistic children.

AB - Platelet monoamine oxidase (MAO) activity was studied in 31 individuals suffering from early childhood autism and was not significantly different from that found in normal children or adults. In the autistic children, MAO activity decreased with age, and there was a trend toward greater platelet MAO activity in prepubertal and pubertal male autistic children relative to normal male children. Total platelet counts were not elevated in autistic children.

UR - https://www.scopus.com/pages/publications/0017374449

U2 - 10.1001/archpsyc.1977.01770170044003

DO - 10.1001/archpsyc.1977.01770170044003

M3 - Article

C2 - 871232

AN - SCOPUS:0017374449

SN - 0003-990X

VL - 34

SP - 534

EP - 537

JO - Archives of General Psychiatry

JF - Archives of General Psychiatry

IS - 5

ER -

Platelet Monoamine Oxidase in Early Childhood Autism

Abstract

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