Physicochemical aspects of drug release from poloxamer block copolymer gels

Yang Lin; Suddhas Talukdar; Paschalis Alexandridis

Physicochemical aspects of drug release from poloxamer block copolymer gels

Yang Lin
, Suddhas Talukdar
, Paschalis Alexandridis

Department of Chemical and Biological Engineering

SUNY Buffalo

Research output: Contribution to journal › Conference article › peer-review

2 Scopus citations

Abstract

The effects of Poloxamer hydrogel formulation parameters on the drug release kinetics were studied, focusing on the diffusion vs. erosion contribution to the overall drug release. In particular, the Poloxamer hydrogel formulation was varied by changing the Poloxamer concentration and the drug loading in the hydrogel formulation. The rheological properties of the Poloxamer gels with varying Poloxamer concentration and drug loading were monitored. The rheology data revealed that at higher Poloxamer concentrations, a stronger gel forms.

Original language	English
Pages (from-to)	1703-1704
Number of pages	2
Journal	American Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume	41
Issue number	2
State	Published - Aug 2000
Event	Washington,DC. Meeting - Washington, DC, USA Duration: Aug 20 2000 → Aug 24 2000

Cite this

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title = "Physicochemical aspects of drug release from poloxamer block copolymer gels",

abstract = "The effects of Poloxamer hydrogel formulation parameters on the drug release kinetics were studied, focusing on the diffusion vs. erosion contribution to the overall drug release. In particular, the Poloxamer hydrogel formulation was varied by changing the Poloxamer concentration and the drug loading in the hydrogel formulation. The rheological properties of the Poloxamer gels with varying Poloxamer concentration and drug loading were monitored. The rheology data revealed that at higher Poloxamer concentrations, a stronger gel forms.",

author = "Yang Lin and Suddhas Talukdar and Paschalis Alexandridis",

year = "2000",

month = aug,

language = "English",

volume = "41",

pages = "1703--1704",

journal = "American Chemical Society, Polymer Preprints, Division of Polymer Chemistry",

issn = "0032-3934",

number = "2",

note = "Washington,DC. Meeting ; Conference date: 20-08-2000 Through 24-08-2000",

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TY - JOUR

T1 - Physicochemical aspects of drug release from poloxamer block copolymer gels

AU - Lin, Yang

AU - Talukdar, Suddhas

AU - Alexandridis, Paschalis

PY - 2000/8

Y1 - 2000/8

N2 - The effects of Poloxamer hydrogel formulation parameters on the drug release kinetics were studied, focusing on the diffusion vs. erosion contribution to the overall drug release. In particular, the Poloxamer hydrogel formulation was varied by changing the Poloxamer concentration and the drug loading in the hydrogel formulation. The rheological properties of the Poloxamer gels with varying Poloxamer concentration and drug loading were monitored. The rheology data revealed that at higher Poloxamer concentrations, a stronger gel forms.

AB - The effects of Poloxamer hydrogel formulation parameters on the drug release kinetics were studied, focusing on the diffusion vs. erosion contribution to the overall drug release. In particular, the Poloxamer hydrogel formulation was varied by changing the Poloxamer concentration and the drug loading in the hydrogel formulation. The rheological properties of the Poloxamer gels with varying Poloxamer concentration and drug loading were monitored. The rheology data revealed that at higher Poloxamer concentrations, a stronger gel forms.

UR - https://www.scopus.com/pages/publications/0034250472

M3 - Conference article

AN - SCOPUS:0034250472

SN - 0032-3934

VL - 41

SP - 1703

EP - 1704

JO - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

JF - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

IS - 2

T2 - Washington,DC. Meeting

Y2 - 20 August 2000 through 24 August 2000

ER -

Physicochemical aspects of drug release from poloxamer block copolymer gels

Abstract

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